Effect of prostaglandin E2 upon release of pancreatic somatostatin-like immunoreactivity

V. Schusdziarra, D. Rouiller, V. Harris, T. Wasada, Roger H Unger

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Infusion of prostaglandin E2 (1 ug/kg/min) in six normal dogs elicited a greater than two-fold rise in pancreaticoduodenal vein somatostatin-like immunoreactivity. Insulin and glucagon also rose. The results raise the possibility that the function of the canine pancreatic D-cell is under prostaglandinergic influence.

Original languageEnglish (US)
Pages (from-to)2099-2102
Number of pages4
JournalLife Sciences
Issue number19
StatePublished - May 11 1981

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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