Effect of topical nasal steroid sprays on nasal mucosa and ciliary function

D. J. Verret, Bradley F. Marple

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Purpose of review: This review was conducted to examine current evidence focusing on the effect of nasal steroid sprays on nasal ciliary function. Recent findings: Review of current literature suggests that long term effects of topical corticosteroid nasal sprays are safe and fail to cause damage to local nasal structure and function. Summary: The use of corticosteroid nasal sprays for the treatment of allergic rhinitis is widely accepted. Popularity of this class of medications is based on a well-established combination of efficacy, tolerability, and safety. Although current literature suggests that the use of intranasal steroids is indeed safe, increasing indications for prolonged administration continue to fuel debate regarding the long-term effect on local nasal structure and function. The purpose of this article is to review current literature addressing the effects of the components of local intranasal steroid sprays on the structure and function of the nasal mucosa.

Original languageEnglish (US)
Pages (from-to)14-18
Number of pages5
JournalCurrent Opinion in Otolaryngology and Head and Neck Surgery
Volume13
Issue number1
DOIs
StatePublished - Feb 2005

Fingerprint

Nasal Sprays
Nasal Mucosa
Nose
Steroids
Adrenal Cortex Hormones
Safety

Keywords

  • Allergic rhinitis
  • Nasal ciliary clearance
  • Nasal mucociliary transport
  • Nasal steroid sprays

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery

Cite this

Effect of topical nasal steroid sprays on nasal mucosa and ciliary function. / Verret, D. J.; Marple, Bradley F.

In: Current Opinion in Otolaryngology and Head and Neck Surgery, Vol. 13, No. 1, 02.2005, p. 14-18.

Research output: Contribution to journalArticle

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