Effects of T's and blues abuse on pregnancy outcome and infant health status

B. B. Little, L. M. Snell, J. D. Breckenridge, K. A. Knoll, V. R. Klein, L. C. Gilstrap

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

T's and blues (pentazocine and tripelennamine) abuse during pregnancy has been reported to be associated with adverse maternal and fetal effects. In this study, conducted at Parkland Memorial Hospital in Dallas, Texas, pregnancy outcome and health status of infants born to 23 T's and blues abusers were compared to a group of 100 unexposed women and their infants. Infants born to T's and blues abusers had significantly reduced birthweight, length, head circumference, and an increased frequency of major congenital anomalies (3 of 23), including two congenital cardiac anomalies. However, one of these cardiac anomalies occurred in the offspring of a woman who also reported moderate to heavy daily alcohol use during pregnancy. The other cardiac anomaly occurred in association with in utero anoxia. We therefore surmise that a known teratogen (alcohol) and perinatal complications caused two of the major anomalies, and not the pentazocine-tripelennamine combination per se.

Original languageEnglish (US)
Pages (from-to)359-362
Number of pages4
JournalAmerican Journal of Perinatology
Volume7
Issue number4
StatePublished - 1990

Fingerprint

Tripelennamine
Pregnancy Outcome
Health Status
Pentazocine
Alcohols
Teratogens
Pregnancy
Head
Infant Health

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Little, B. B., Snell, L. M., Breckenridge, J. D., Knoll, K. A., Klein, V. R., & Gilstrap, L. C. (1990). Effects of T's and blues abuse on pregnancy outcome and infant health status. American Journal of Perinatology, 7(4), 359-362.

Effects of T's and blues abuse on pregnancy outcome and infant health status. / Little, B. B.; Snell, L. M.; Breckenridge, J. D.; Knoll, K. A.; Klein, V. R.; Gilstrap, L. C.

In: American Journal of Perinatology, Vol. 7, No. 4, 1990, p. 359-362.

Research output: Contribution to journalArticle

Little, BB, Snell, LM, Breckenridge, JD, Knoll, KA, Klein, VR & Gilstrap, LC 1990, 'Effects of T's and blues abuse on pregnancy outcome and infant health status', American Journal of Perinatology, vol. 7, no. 4, pp. 359-362.
Little BB, Snell LM, Breckenridge JD, Knoll KA, Klein VR, Gilstrap LC. Effects of T's and blues abuse on pregnancy outcome and infant health status. American Journal of Perinatology. 1990;7(4):359-362.
Little, B. B. ; Snell, L. M. ; Breckenridge, J. D. ; Knoll, K. A. ; Klein, V. R. ; Gilstrap, L. C. / Effects of T's and blues abuse on pregnancy outcome and infant health status. In: American Journal of Perinatology. 1990 ; Vol. 7, No. 4. pp. 359-362.
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