Efficient N-arylation of pyridazin-3(2H)-ones

Jeum Jong Kim; Yong Dae Park; Su Dong Cho; Ho Kyun Kim; Hyun A. Chung; Sang Gyeong Lee; J. R. Falck; Yong Jin Yoon

doi:10.1016/j.tetlet.2004.10.003

Efficient N-arylation of pyridazin-3(2H)-ones

Jeum Jong Kim, Yong Dae Park, Su Dong Cho, Ho Kyun Kim, Hyun A. Chung, Sang Gyeong Lee, J. R. Falck, Yong Jin Yoon

Biochemistry

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene. A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene.

Original language	English (US)
Pages (from-to)	8781-8784
Number of pages	4
Journal	Tetrahedron Letters
Volume	45
Issue number	48
DOIs	https://doi.org/10.1016/j.tetlet.2004.10.003
State	Published - Nov 22 2004

Keywords

Lead tetraacetate
N-Arylation
Pyridazin-3(2H)-ones
Zinc chloride

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2004.10.003

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title = "Efficient N-arylation of pyridazin-3(2H)-ones",

abstract = "A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene. A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene.",

keywords = "Lead tetraacetate, N-Arylation, Pyridazin-3(2H)-ones, Zinc chloride",

author = "Kim, {Jeum Jong} and Park, {Yong Dae} and Cho, {Su Dong} and Kim, {Ho Kyun} and Chung, {Hyun A.} and Lee, {Sang Gyeong} and Falck, {J. R.} and Yoon, {Yong Jin}",

note = "Funding Information: This work was supported by a grant from the Korea Science and Engineering Foundation (KOSEF) to the Environmental Biotechnology National Core Research Center (grant #: R15-2003-012-02001-0). ",

year = "2004",

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day = "22",

doi = "10.1016/j.tetlet.2004.10.003",

language = "English (US)",

volume = "45",

pages = "8781--8784",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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number = "48",

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T1 - Efficient N-arylation of pyridazin-3(2H)-ones

AU - Kim, Jeum Jong

AU - Park, Yong Dae

AU - Cho, Su Dong

AU - Kim, Ho Kyun

AU - Chung, Hyun A.

AU - Lee, Sang Gyeong

AU - Falck, J. R.

AU - Yoon, Yong Jin

N1 - Funding Information: This work was supported by a grant from the Korea Science and Engineering Foundation (KOSEF) to the Environmental Biotechnology National Core Research Center (grant #: R15-2003-012-02001-0).

PY - 2004/11/22

Y1 - 2004/11/22

N2 - A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene. A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene.

AB - A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene. A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene.

KW - Lead tetraacetate

KW - N-Arylation

KW - Pyridazin-3(2H)-ones

KW - Zinc chloride

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DO - 10.1016/j.tetlet.2004.10.003

M3 - Article

AN - SCOPUS:7444270527

SN - 0040-4039

VL - 45

SP - 8781

EP - 8784

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 48

ER -

Efficient N-arylation of pyridazin-3(2H)-ones

Abstract

Keywords

ASJC Scopus subject areas

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