Elevated White Blood Cell Levels and Thrombotic Events in Patients With Polycythemia Vera: A Real-World Analysis of Veterans Health Administration Data

Shreekant Parasuraman, Jingbo Yu, Dilan Paranagama, Sulena Shrestha, Li Wang, Onur Baser, Robyn Scherber

Research output: Contribution to journalArticle

Abstract

Patients with polycythemia vera (PV) have a substantial risk of thrombotic events (TEs). In the present retrospective analysis using Veterans Health Administration claims data, 25% of 1565 patients experienced a TE during follow-up. We observed a positive, significant association between white blood cell (WBC) counts ≥ 8.5 × 109/L and TE occurrence (reference, WBC count < 7.0 × 109/L), supporting continued inclusion of WBC count control in disease management.

Original languageEnglish (US)
Pages (from-to)63-69
Number of pages7
JournalClinical Lymphoma, Myeloma and Leukemia
Volume20
Issue number2
DOIs
StatePublished - Feb 2020
Externally publishedYes

Keywords

  • Leukocytosis
  • Retrospective analysis
  • Thrombosis
  • White blood cell count

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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