Elevated White Blood Cell Levels and Thrombotic Events in Patients With Polycythemia Vera: A Real-World Analysis of Veterans Health Administration Data

Shreekant Parasuraman; Jingbo Yu; Dilan Paranagama; Sulena Shrestha; Li Wang; Onur Baser; Robyn Scherber

doi:10.1016/j.clml.2019.11.010

Elevated White Blood Cell Levels and Thrombotic Events in Patients With Polycythemia Vera: A Real-World Analysis of Veterans Health Administration Data

Shreekant Parasuraman, Jingbo Yu, Dilan Paranagama, Sulena Shrestha, Li Wang, Onur Baser, Robyn Scherber

Research output: Contribution to journal › Article

Abstract

Patients with polycythemia vera (PV) have a substantial risk of thrombotic events (TEs). In the present retrospective analysis using Veterans Health Administration claims data, 25% of 1565 patients experienced a TE during follow-up. We observed a positive, significant association between white blood cell (WBC) counts ≥ 8.5 × 10⁹/L and TE occurrence (reference, WBC count < 7.0 × 10⁹/L), supporting continued inclusion of WBC count control in disease management.

Original language	English (US)
Pages (from-to)	63-69
Number of pages	7
Journal	Clinical Lymphoma, Myeloma and Leukemia
Volume	20
Issue number	2
DOIs	https://doi.org/10.1016/j.clml.2019.11.010
State	Published - Feb 2020
Externally published	Yes

Keywords

Leukocytosis
Retrospective analysis
Thrombosis
White blood cell count

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

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Parasuraman, S., Yu, J., Paranagama, D., Shrestha, S., Wang, L., Baser, O., & Scherber, R. (2020). Elevated White Blood Cell Levels and Thrombotic Events in Patients With Polycythemia Vera: A Real-World Analysis of Veterans Health Administration Data. Clinical Lymphoma, Myeloma and Leukemia, 20(2), 63-69. https://doi.org/10.1016/j.clml.2019.11.010

Elevated White Blood Cell Levels and Thrombotic Events in Patients With Polycythemia Vera : A Real-World Analysis of Veterans Health Administration Data. / Parasuraman, Shreekant; Yu, Jingbo; Paranagama, Dilan; Shrestha, Sulena; Wang, Li; Baser, Onur; Scherber, Robyn.

In: Clinical Lymphoma, Myeloma and Leukemia, Vol. 20, No. 2, 02.2020, p. 63-69.

Research output: Contribution to journal › Article

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