TY - JOUR
T1 - Elevated White Blood Cell Levels and Thrombotic Events in Patients With Polycythemia Vera
T2 - A Real-World Analysis of Veterans Health Administration Data
AU - Parasuraman, Shreekant
AU - Yu, Jingbo
AU - Paranagama, Dilan
AU - Shrestha, Sulena
AU - Wang, Li
AU - Baser, Onur
AU - Scherber, Robyn
N1 - Funding Information:
The present study and writing support were funded by Incyte Corporation (Wilmington, DE). The study design and data collection, analysis, and interpretation were conducted by us, some of whom are employees of Incyte Corporation. Editorial assistance was provided by Wendy van der Spuy, PhD (Complete Healthcare Communications, LLC [North Wales, PA], a CHC Group Company).
Publisher Copyright:
© 2019 The Authors
PY - 2020/2
Y1 - 2020/2
N2 - Patients with polycythemia vera (PV) have a substantial risk of thrombotic events (TEs). In the present retrospective analysis using Veterans Health Administration claims data, 25% of 1565 patients experienced a TE during follow-up. We observed a positive, significant association between white blood cell (WBC) counts ≥ 8.5 × 109/L and TE occurrence (reference, WBC count < 7.0 × 109/L), supporting continued inclusion of WBC count control in disease management.
AB - Patients with polycythemia vera (PV) have a substantial risk of thrombotic events (TEs). In the present retrospective analysis using Veterans Health Administration claims data, 25% of 1565 patients experienced a TE during follow-up. We observed a positive, significant association between white blood cell (WBC) counts ≥ 8.5 × 109/L and TE occurrence (reference, WBC count < 7.0 × 109/L), supporting continued inclusion of WBC count control in disease management.
KW - Leukocytosis
KW - Retrospective analysis
KW - Thrombosis
KW - White blood cell count
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U2 - 10.1016/j.clml.2019.11.010
DO - 10.1016/j.clml.2019.11.010
M3 - Article
C2 - 31865003
AN - SCOPUS:85076827331
VL - 20
SP - 63
EP - 69
JO - Clinical Lymphoma, Myeloma and Leukemia
JF - Clinical Lymphoma, Myeloma and Leukemia
SN - 2152-2669
IS - 2
ER -