Several new devices offer the prospect of robust and durable endoscopic closure of acute and chronic GI wall defects, including spontaneous and iatrogenic perforations, anastomotic leaks, and chronic fistulae. They may also allow satisfactory closure of enterotomies created for NOTES procedures. The OTSC and Overstitch systems are currently being marketed in the United States. Case series have demonstrated the effectiveness of the OTSC in the closure of acute defects. Its efficacy in chronic fistulae may be partially impaired by the difficulties in approximating indurated, fibrotic tissue for closure. The Overstitch device is more complex to use and is not suited for smaller lumens. However, it offers the potential advantages of being able to close larger or more chronic defects. Further prospective studies are needed to define the role of these devices in the closure of GI wall defects.
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging