Enteric pathogens exploit the microbiota-generated nutritional environment of the gut

Alline R. Pacheco, Vanessa Sperandio

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The mammalian gastrointestinal (GI) tract harbors a diverse collection of indigenous bacteria known as the microbiota. The number of bacterial cells within our bodies exceeds the number of our cells by one order of magnitude (3). Homeostasis of the microbiota is maintained by differential nutrient utilization and physical separation from the gut mucosa (4). However, environmental perturbations such as antibiotic treatment, changes in diet, and infection lead to substantial alterations in composition and structure of the microbiota, referred to as dysbiosis (5 - 8).

Original languageEnglish (US)
Title of host publicationMetabolism and Bacterial Pathogenesis
PublisherWiley-Blackwell
Pages279-296
Number of pages18
ISBN (Electronic)9781683670926
ISBN (Print)9781555818869
DOIs
StatePublished - Aug 4 2015

Keywords

  • EHEC
  • Enteric pathogen
  • Ethanolamine
  • Gut microbiota
  • Locus of enterocyte effacement
  • Stratified mucus layer
  • TTSS

ASJC Scopus subject areas

  • Immunology and Microbiology(all)

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