Epithelioid hemangioendothelioma of the liver disseminated to the peritoneum treated with liver transplantation and interferon alpha-2b

Liise K. Kayler, Robert M. Merion, Juan D. Arenas, John C. Magee, Darrell A. Campbell, Steven M. Rudich, Jeffrey D. Punch

Research output: Contribution to journalArticle

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Abstract

Epithelioid hemangioendothelioma (EH) is a rare, low-grade, malignant neoplasm of vascular origin that may develop at different sites, such as in the soft tissue, lungs, or liver. We report the case of a 21-year-old female with primary EH of the liver treated by liver transplantation and review the available literature on EH. This patient developed symptomatic recurrence of the tumor in the pelvis 2 months posttransplant. Treatment with interferon alpha-2b resulted in substantial regression of the pelvic metastases and alleviation of symptoms, but the patient developed graft rejection and died of associated complications 16 months posttransplant. This report is the first showing the efficacy of interferon in this setting.

Original languageEnglish (US)
Pages (from-to)128-130
Number of pages3
JournalTransplantation
Volume74
Issue number1
StatePublished - Jul 15 2002

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interferon alfa-2b
Epithelioid Hemangioendothelioma
Peritoneum
Liver Transplantation
Liver
Vascular Neoplasms
Graft Rejection
Pelvis
Interferons
Neoplasm Metastasis
Recurrence
Lung
Neoplasms

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Kayler, L. K., Merion, R. M., Arenas, J. D., Magee, J. C., Campbell, D. A., Rudich, S. M., & Punch, J. D. (2002). Epithelioid hemangioendothelioma of the liver disseminated to the peritoneum treated with liver transplantation and interferon alpha-2b. Transplantation, 74(1), 128-130.

Epithelioid hemangioendothelioma of the liver disseminated to the peritoneum treated with liver transplantation and interferon alpha-2b. / Kayler, Liise K.; Merion, Robert M.; Arenas, Juan D.; Magee, John C.; Campbell, Darrell A.; Rudich, Steven M.; Punch, Jeffrey D.

In: Transplantation, Vol. 74, No. 1, 15.07.2002, p. 128-130.

Research output: Contribution to journalArticle

Kayler, LK, Merion, RM, Arenas, JD, Magee, JC, Campbell, DA, Rudich, SM & Punch, JD 2002, 'Epithelioid hemangioendothelioma of the liver disseminated to the peritoneum treated with liver transplantation and interferon alpha-2b', Transplantation, vol. 74, no. 1, pp. 128-130.
Kayler, Liise K. ; Merion, Robert M. ; Arenas, Juan D. ; Magee, John C. ; Campbell, Darrell A. ; Rudich, Steven M. ; Punch, Jeffrey D. / Epithelioid hemangioendothelioma of the liver disseminated to the peritoneum treated with liver transplantation and interferon alpha-2b. In: Transplantation. 2002 ; Vol. 74, No. 1. pp. 128-130.
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