European patients with benign prostatic hyperplasia (BPH): Differences in sexual dysfunction

Roger Kirby, Claus Roehrborn, Peter Boyle, Alain Jardin

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INTRODUCTION: This study examined the relationship between cultural background and sexual dysfunction in BPH patients, from five European countries, enrolled into the Prospective European Doxazosin and Combination Trial (PREDICT). PATIENTS AND METHODS: The study investigated 826 patients, from France, Germany, Italy, the Netherlands and the UK. Patients were aged > 48 years with an International Prostatic Symptom Score (I-PSS) > 12 and peak urinary flow rate (Qmax) < 15 ml/sec. At study entry, general questions on sexual activity (sexually active, wish to be sexually active, regular panner) were asked during patient interview, then patients completed questionnaires on aspects of sexual dysfunction, in terms of frequency of problems (scale of 1 to 4, from once a month to almost always) and bothersomeness (scale of 0 to 4. from not at all to extremely). RESULTS: No statistical differences in BPH severity between countries were observed Although there were no differences in patients' desire to be sexually active, there were differences in actual activity (p<0.05; I, F vs. UK, G, NL) and presence of a regular partner (p<0.05, I, F, G vs. UK, NL). In all countries frequencies of sexual dysfunctions were high, with the most in Netherlands and the least in France, but, by contrast, bothersomeness was greatest in France and least in the Netherlands (Table). The frequency (F) and bothersomeness (B) scores were as follows: Sexual dysfunction France Germany Holland Italy UK F B F B F B F B F B Reduced sexual interest 2.5 1.6 2.2 1.3 2.6 0.6 2.2 0.8 2.6 1.1 Problems with: Gaining erection 2.3 1.9 2.7 1.7 2.9 0.6 2.4 1.2 2.8 1.1 Keeping erection 2.3 2.0 2.8 1.7 3.0 0.9 2.2 1.0 2.8 1.6 Completing act 2.3 1.8 2.5 1.4 2.1 0.8 2.4 1.5 2.6 1.5 Deriving satisfaction 2.3 1.6 2.4 1.4 2.8 0.7 2.4 1.2 2.6 1.7 CONCLUSIONS: This study recruited a large population of BPH patients from throughout Europe. There appears to be a large burden of sexual dysfunction in the BPH patient population, and there is considerable variation between countries.

Original languageEnglish (US)
Number of pages1
JournalBritish Journal of Urology
Issue numberSUPPL. 2
StatePublished - Dec 1 1997

ASJC Scopus subject areas

  • Urology


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