Evidence that the sigma 1 protein of reovirus serotype 3 is a multimer

R. Bassel-Duby, M. L. Nibert, C. J. Homcy, B. N. Fields, D. G. Sawutz

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

In this report, we study the reovirus serotype 3 (strain Dearing) σ1 protein obtained from various sources: from Escherichia coli expressing σ1 protein, from reovirus-infected mouse L cells, and from purified reovirions. We demonstrate that the σ1 protein is a multimer in its undisrupted form and present biochemical evidence suggesting that the multimer is made up of four σ1 subunits.

Original languageEnglish (US)
Pages (from-to)1834-1841
Number of pages8
JournalJournal of virology
Volume61
Issue number6
DOIs
StatePublished - 1987

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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