Exploring feasibility of multicolored CdTe quantum dots for in Vitro and in Vivo fluorescent imaging

Junfeng Su, Jun Zhang, Li Liu, Yalou Huang, Ralph P. Mason

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

We report the use of novel multicolored CdTe quantum dots (QDs) as fluorophores for biological fluorescence imaging. The CdTe QDs were prepared to exhibit emission wavelengths in the green, yellow, and red range by using trifluoroacetic acid (TFA), L-cysteine and thioglycolic acid (TGA) as surface stabilizers, respectively. The particles have good water solubility and photostability. Fluorescence imaging potential was evaluated in vitro and in vivo using a multispectral Maestro CRI Fluorescence Imaging system. The results show that different colored CdTe QDs allow sensitive detection simultaneously or separately both in vitro and in vivo against background fluorescence. The studies indicate that CdTe QDs can provide alternative fluorescent probes for biological imaging.

Original languageEnglish (US)
Pages (from-to)1174-1177
Number of pages4
JournalJournal of Nanoscience and Nanotechnology
Volume8
Issue number3
DOIs
StatePublished - Mar 1 2008

Keywords

  • Biological application
  • CdTe
  • Fluorescent imaging
  • Quantum dots

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)
  • Condensed Matter Physics

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