Extramedullary hematopoiesis in unusual locations in hematologically compromised and noncompromised patients

Prabhakar Rajiah, Riku Hayashi, Thomas W. Bauer, Murali Sundaram

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Extramedullary hematopoiesis (EMH) occurs as a compensatory reaction to an underlying hematologic abnormality. EMH is most commonly seen in the liver and spleen but rarely has been reported in other locations, as well. On rare occasions, EMH may mimic a neoplasm in hematologically noncompromised patients. In this report, we present three cases of EMH in unusual locations, two in the presacral soft tissue and one in the synovial lining of the knee joint. The patients with presacral masses had no hematologic abnormality. In all patients with EMH, imaging plays an important role in both localization of the lesion and guidance for the biopsy; when imaging results are correlated with histological findings, the diagnosis of EMH can be confirmed.

Original languageEnglish (US)
Pages (from-to)947-953
Number of pages7
JournalSkeletal Radiology
Volume40
Issue number7
DOIs
StatePublished - Jul 1 2011

Fingerprint

Extramedullary Hematopoiesis
Knee Joint
Spleen
Biopsy
Liver

Keywords

  • Extramedullary hematopoiesis
  • MRI
  • Presacral
  • Synovial

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Extramedullary hematopoiesis in unusual locations in hematologically compromised and noncompromised patients. / Rajiah, Prabhakar; Hayashi, Riku; Bauer, Thomas W.; Sundaram, Murali.

In: Skeletal Radiology, Vol. 40, No. 7, 01.07.2011, p. 947-953.

Research output: Contribution to journalArticle

Rajiah, Prabhakar ; Hayashi, Riku ; Bauer, Thomas W. ; Sundaram, Murali. / Extramedullary hematopoiesis in unusual locations in hematologically compromised and noncompromised patients. In: Skeletal Radiology. 2011 ; Vol. 40, No. 7. pp. 947-953.
@article{7a9011aefb394fe4bbf4552fd8347105,
title = "Extramedullary hematopoiesis in unusual locations in hematologically compromised and noncompromised patients",
abstract = "Extramedullary hematopoiesis (EMH) occurs as a compensatory reaction to an underlying hematologic abnormality. EMH is most commonly seen in the liver and spleen but rarely has been reported in other locations, as well. On rare occasions, EMH may mimic a neoplasm in hematologically noncompromised patients. In this report, we present three cases of EMH in unusual locations, two in the presacral soft tissue and one in the synovial lining of the knee joint. The patients with presacral masses had no hematologic abnormality. In all patients with EMH, imaging plays an important role in both localization of the lesion and guidance for the biopsy; when imaging results are correlated with histological findings, the diagnosis of EMH can be confirmed.",
keywords = "Extramedullary hematopoiesis, MRI, Presacral, Synovial",
author = "Prabhakar Rajiah and Riku Hayashi and Bauer, {Thomas W.} and Murali Sundaram",
year = "2011",
month = "7",
day = "1",
doi = "10.1007/s00256-011-1129-z",
language = "English (US)",
volume = "40",
pages = "947--953",
journal = "Skeletal Radiology",
issn = "0364-2348",
publisher = "Springer Verlag",
number = "7",

}

TY - JOUR

T1 - Extramedullary hematopoiesis in unusual locations in hematologically compromised and noncompromised patients

AU - Rajiah, Prabhakar

AU - Hayashi, Riku

AU - Bauer, Thomas W.

AU - Sundaram, Murali

PY - 2011/7/1

Y1 - 2011/7/1

N2 - Extramedullary hematopoiesis (EMH) occurs as a compensatory reaction to an underlying hematologic abnormality. EMH is most commonly seen in the liver and spleen but rarely has been reported in other locations, as well. On rare occasions, EMH may mimic a neoplasm in hematologically noncompromised patients. In this report, we present three cases of EMH in unusual locations, two in the presacral soft tissue and one in the synovial lining of the knee joint. The patients with presacral masses had no hematologic abnormality. In all patients with EMH, imaging plays an important role in both localization of the lesion and guidance for the biopsy; when imaging results are correlated with histological findings, the diagnosis of EMH can be confirmed.

AB - Extramedullary hematopoiesis (EMH) occurs as a compensatory reaction to an underlying hematologic abnormality. EMH is most commonly seen in the liver and spleen but rarely has been reported in other locations, as well. On rare occasions, EMH may mimic a neoplasm in hematologically noncompromised patients. In this report, we present three cases of EMH in unusual locations, two in the presacral soft tissue and one in the synovial lining of the knee joint. The patients with presacral masses had no hematologic abnormality. In all patients with EMH, imaging plays an important role in both localization of the lesion and guidance for the biopsy; when imaging results are correlated with histological findings, the diagnosis of EMH can be confirmed.

KW - Extramedullary hematopoiesis

KW - MRI

KW - Presacral

KW - Synovial

UR - http://www.scopus.com/inward/record.url?scp=79959947578&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79959947578&partnerID=8YFLogxK

U2 - 10.1007/s00256-011-1129-z

DO - 10.1007/s00256-011-1129-z

M3 - Article

C2 - 21340448

AN - SCOPUS:79959947578

VL - 40

SP - 947

EP - 953

JO - Skeletal Radiology

JF - Skeletal Radiology

SN - 0364-2348

IS - 7

ER -