Femoropopliteal artery stent thrombosis: Report from the excellence in peripheral artery disease registry

Subhash Banerjee, Karan Sarode, Atif Mohammad, Osvaldo Gigliotti, Mirza S. Baig, Shirling Tsai, Nicolas W. Shammas, Anand Prasad, Mazen Abu-Fadel, Andrew Klein, Ehrin J. Armstrong, Haekyung Jeon-Slaughter, Emmanouil S. Brilakis, Deepak L. Bhatt

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Background - There are limited data on femoropopliteal artery stent thrombosis (ST), which is a serious adverse outcome of peripheral artery interventions. Methods and Results - Index procedures resulting in femoropopliteal ST were compared with stent procedures without subsequent ST in the Excellence in Peripheral Artery Disease registry. The study data had a total of 724 cases of stent procedures and 604 unique patients. Femoropopliteal ST occurred in 26 of 604 patients (4.3%) over a median follow-up of 6 months post procedure. ST was more likely to occur in men (96.3% versus 82.2%; P=0.026) and to have an initial intervention for chronic total occlusions (88.5% versus 64.0%; P=0.01). There was no significant difference in ST between drug-coated and bare-metal stents (4.4% versus 3.4%; P=0.55), but the rate of ST was significantly higher with self-expanding covered stent grafts compared with bare-metal stents (10.6% versus 3.4%; P=0.02). ST was significantly associated with an increased risk of 12-month major adverse limb events (hazard ratio, 4.99; 95% confidence interval, 2.31-10.77; P

Original languageEnglish (US)
Article numbere002730
JournalCirculation: Cardiovascular Interventions
Volume9
Issue number2
DOIs
StatePublished - Feb 1 2016

Keywords

  • Confidence intervals
  • Odds ratio
  • Peripheral artery disease
  • Stent
  • Thrombosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Banerjee, S., Sarode, K., Mohammad, A., Gigliotti, O., Baig, M. S., Tsai, S., Shammas, N. W., Prasad, A., Abu-Fadel, M., Klein, A., Armstrong, E. J., Jeon-Slaughter, H., Brilakis, E. S., & Bhatt, D. L. (2016). Femoropopliteal artery stent thrombosis: Report from the excellence in peripheral artery disease registry. Circulation: Cardiovascular Interventions, 9(2), [e002730]. https://doi.org/10.1161/CIRCINTERVENTIONS.115.002730