Flourine-19 NMR spectroscopy and imaging investigations of myocardial perfusion and cardiac function

Ray L. Nunnally, Evelyn E Babcock, Sherye D. Horner, Ronald M Peshock

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Fluorine-19 nuclear magnetic resonance images of rabbit hearts have been obtained with the administration of a fluorinated contrast compound. The use of fluorine-labeled compounds allows differences in tissue perfusion to be demonstrated between hearts with and without coronary artery ligation. In postischemic reperfusion studies, regional hypoperfusion is also demonstrated by 19F imaging. The results of in vivo rabbit studies show that 19F NMR can be used to monitor the rate of blood pool and extravascular space dilution of a single bolus injection of either a water soluble or emulsified fluorine-labeled agent.

Original languageEnglish (US)
Pages (from-to)399-405
Number of pages7
JournalMagnetic Resonance Imaging
Volume3
Issue number4
DOIs
StatePublished - 1985

Fingerprint

Fluorine
rabbits
Nuclear magnetic resonance spectroscopy
fluorine
Fluorine Compounds
Magnetic Resonance Spectroscopy
Fluorine compounds
Perfusion
fluorine compounds
Magnetic Resonance Imaging
Nuclear magnetic resonance
Rabbits
nuclear magnetic resonance
arteries
spectroscopy
Dilution
Reperfusion
blood
Ligation
dilution

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Flourine-19 NMR spectroscopy and imaging investigations of myocardial perfusion and cardiac function. / Nunnally, Ray L.; Babcock, Evelyn E; Horner, Sherye D.; Peshock, Ronald M.

In: Magnetic Resonance Imaging, Vol. 3, No. 4, 1985, p. 399-405.

Research output: Contribution to journalArticle

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