Abstract
A small animal whole body imaging cylindrical device was built with plastic scintillating fibers and position sensitive photomultipliers (Hamamatsu) and digitized using flash ADCs. A co-axial brass mesh collimator (septum thickness 1 mm) was used in combination with an electronic collimation scheme to enhance spatial resolution. Imaging studies with 125I labeled folic acid were performed in mice bearing folate receptor +ve (IGROV) tumor and receptor -ve (Meth-A) tumor. In-situ imaging of animals sacrificed at 15-30 min post injection of the tracer showed the localization of the tumor in animals with the folate receptor +ve tumors. Our initial studies demonstrate the utility of a device built with plastic scintillating fibers in small animal imaging studies with low energy photons (25-35 keV).
Original language | English (US) |
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Pages (from-to) | 800-803 |
Number of pages | 4 |
Journal | Nuclear Inst. and Methods in Physics Research, B |
Volume | 99 |
Issue number | 1-4 |
DOIs | |
State | Published - May 5 1995 |
ASJC Scopus subject areas
- Nuclear and High Energy Physics
- Instrumentation