From friend to foe: Pro-apoptotic action of nuclear ARC in diabetes

Toshiharu Onodera; Philipp E. Scherer

doi:10.1016/j.devcel.2021.03.001

From friend to foe: Pro-apoptotic action of nuclear ARC in diabetes

Toshiharu Onodera, Philipp E. Scherer

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Apoptosis repressor with caspase recruitment domain (ARC) is an established cytoplasmic anti-apoptotic factor relevant for cancer and metabolic disease. In this issue of Developmental Cell, McKimpson et al. show that ARC can assume potent pro-apoptotic effects in β cells of the endocrine pancreas via translocation to the nucleus.

Original language	English (US)
Pages (from-to)	717-718
Number of pages	2
Journal	Developmental cell
Volume	56
Issue number	6
DOIs	https://doi.org/10.1016/j.devcel.2021.03.001
State	Published - Mar 22 2021

ASJC Scopus subject areas

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
Developmental Biology
Cell Biology

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10.1016/j.devcel.2021.03.001

Cite this

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abstract = "Apoptosis repressor with caspase recruitment domain (ARC) is an established cytoplasmic anti-apoptotic factor relevant for cancer and metabolic disease. In this issue of Developmental Cell, McKimpson et al. show that ARC can assume potent pro-apoptotic effects in β cells of the endocrine pancreas via translocation to the nucleus.",

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From friend to foe: Pro-apoptotic action of nuclear ARC in diabetes

Abstract

ASJC Scopus subject areas

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