From friend to foe: Pro-apoptotic action of nuclear ARC in diabetes

Toshiharu Onodera, Philipp E. Scherer

Research output: Contribution to journalArticlepeer-review

Abstract

Apoptosis repressor with caspase recruitment domain (ARC) is an established cytoplasmic anti-apoptotic factor relevant for cancer and metabolic disease. In this issue of Developmental Cell, McKimpson et al. show that ARC can assume potent pro-apoptotic effects in β cells of the endocrine pancreas via translocation to the nucleus.

Original languageEnglish (US)
Pages (from-to)717-718
Number of pages2
JournalDevelopmental cell
Volume56
Issue number6
DOIs
StatePublished - Mar 22 2021

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'From friend to foe: Pro-apoptotic action of nuclear ARC in diabetes'. Together they form a unique fingerprint.

Cite this