Gait coordination impairment is associated with mobility in older adults

Eric G. James, Suzanne G. Leveille, Tongjian You, Jeffrey M. Hausdorff, Thomas Travison, Brad Manor, Robert McLean, Jonathan F. Bean

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Impairments to body systems contribute to mobility limitations. The objective of this study was to determine whether impaired gait coordination, as measured by the Phase Coordination Index (PCI), is significantly associated with mobility limitations in older adults, even after adjusting for other gait features. Methods: We conducted a cross-sectional analysis of performance-based measures of mobility in older adults (N = 164) 77-101 years of age, participants in the population-based MOBILIZE Boston Study. Mobility outcomes included the Short Physical Performance Battery (SPPB) and each of its three components. Multivariable linear regression models, adjusting for age and gender, were used to examine the associations of PCI and the coefficients of variation of stride length, width and time, stance time, and step width with each outcome. Results: PCI accounted for more variance in SPPB score (R2 = 0.21), gait speed (R2 = 0.17), chair rise score (R2 = 0.10), and balance score (R2 = 0.09) than any of the other gait measures. Impaired gait coordination was significantly associated with performance on the SPPB and each of its component tasks, even after accounting for gait measures previously linked to mobility tasks (all P < 0.05). In multivariable linear regression modeling PCI accounted for an additional 9% of the variance in SPPB score (P < 0.001), after accounting for the other gait variables, age, and gender. Conclusions: This study shows that impaired gait coordination is associated with poorer mobility performance in older adults, independent of other gait variables previously linked to mobility tasks.

Original languageEnglish (US)
Pages (from-to)12-16
Number of pages5
JournalExperimental Gerontology
Volume80
DOIs
StatePublished - Jul 1 2016

Fingerprint

Ataxia
Gait
Linear regression
Mobility Limitation
Linear Models
Cross-Sectional Studies
Population

Keywords

  • Aging
  • Coordination
  • Gait
  • Mobility

ASJC Scopus subject areas

  • Biochemistry
  • Aging
  • Molecular Biology
  • Genetics
  • Endocrinology
  • Cell Biology

Cite this

James, E. G., Leveille, S. G., You, T., Hausdorff, J. M., Travison, T., Manor, B., ... Bean, J. F. (2016). Gait coordination impairment is associated with mobility in older adults. Experimental Gerontology, 80, 12-16. https://doi.org/10.1016/j.exger.2016.04.009

Gait coordination impairment is associated with mobility in older adults. / James, Eric G.; Leveille, Suzanne G.; You, Tongjian; Hausdorff, Jeffrey M.; Travison, Thomas; Manor, Brad; McLean, Robert; Bean, Jonathan F.

In: Experimental Gerontology, Vol. 80, 01.07.2016, p. 12-16.

Research output: Contribution to journalArticle

James, EG, Leveille, SG, You, T, Hausdorff, JM, Travison, T, Manor, B, McLean, R & Bean, JF 2016, 'Gait coordination impairment is associated with mobility in older adults', Experimental Gerontology, vol. 80, pp. 12-16. https://doi.org/10.1016/j.exger.2016.04.009
James, Eric G. ; Leveille, Suzanne G. ; You, Tongjian ; Hausdorff, Jeffrey M. ; Travison, Thomas ; Manor, Brad ; McLean, Robert ; Bean, Jonathan F. / Gait coordination impairment is associated with mobility in older adults. In: Experimental Gerontology. 2016 ; Vol. 80. pp. 12-16.
@article{3d373cf4d9734ad2b0fce7091b79da6b,
title = "Gait coordination impairment is associated with mobility in older adults",
abstract = "Background: Impairments to body systems contribute to mobility limitations. The objective of this study was to determine whether impaired gait coordination, as measured by the Phase Coordination Index (PCI), is significantly associated with mobility limitations in older adults, even after adjusting for other gait features. Methods: We conducted a cross-sectional analysis of performance-based measures of mobility in older adults (N = 164) 77-101 years of age, participants in the population-based MOBILIZE Boston Study. Mobility outcomes included the Short Physical Performance Battery (SPPB) and each of its three components. Multivariable linear regression models, adjusting for age and gender, were used to examine the associations of PCI and the coefficients of variation of stride length, width and time, stance time, and step width with each outcome. Results: PCI accounted for more variance in SPPB score (R2 = 0.21), gait speed (R2 = 0.17), chair rise score (R2 = 0.10), and balance score (R2 = 0.09) than any of the other gait measures. Impaired gait coordination was significantly associated with performance on the SPPB and each of its component tasks, even after accounting for gait measures previously linked to mobility tasks (all P < 0.05). In multivariable linear regression modeling PCI accounted for an additional 9{\%} of the variance in SPPB score (P < 0.001), after accounting for the other gait variables, age, and gender. Conclusions: This study shows that impaired gait coordination is associated with poorer mobility performance in older adults, independent of other gait variables previously linked to mobility tasks.",
keywords = "Aging, Coordination, Gait, Mobility",
author = "James, {Eric G.} and Leveille, {Suzanne G.} and Tongjian You and Hausdorff, {Jeffrey M.} and Thomas Travison and Brad Manor and Robert McLean and Bean, {Jonathan F.}",
year = "2016",
month = "7",
day = "1",
doi = "10.1016/j.exger.2016.04.009",
language = "English (US)",
volume = "80",
pages = "12--16",
journal = "Experimental Gerontology",
issn = "0531-5565",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Gait coordination impairment is associated with mobility in older adults

AU - James, Eric G.

AU - Leveille, Suzanne G.

AU - You, Tongjian

AU - Hausdorff, Jeffrey M.

AU - Travison, Thomas

AU - Manor, Brad

AU - McLean, Robert

AU - Bean, Jonathan F.

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Background: Impairments to body systems contribute to mobility limitations. The objective of this study was to determine whether impaired gait coordination, as measured by the Phase Coordination Index (PCI), is significantly associated with mobility limitations in older adults, even after adjusting for other gait features. Methods: We conducted a cross-sectional analysis of performance-based measures of mobility in older adults (N = 164) 77-101 years of age, participants in the population-based MOBILIZE Boston Study. Mobility outcomes included the Short Physical Performance Battery (SPPB) and each of its three components. Multivariable linear regression models, adjusting for age and gender, were used to examine the associations of PCI and the coefficients of variation of stride length, width and time, stance time, and step width with each outcome. Results: PCI accounted for more variance in SPPB score (R2 = 0.21), gait speed (R2 = 0.17), chair rise score (R2 = 0.10), and balance score (R2 = 0.09) than any of the other gait measures. Impaired gait coordination was significantly associated with performance on the SPPB and each of its component tasks, even after accounting for gait measures previously linked to mobility tasks (all P < 0.05). In multivariable linear regression modeling PCI accounted for an additional 9% of the variance in SPPB score (P < 0.001), after accounting for the other gait variables, age, and gender. Conclusions: This study shows that impaired gait coordination is associated with poorer mobility performance in older adults, independent of other gait variables previously linked to mobility tasks.

AB - Background: Impairments to body systems contribute to mobility limitations. The objective of this study was to determine whether impaired gait coordination, as measured by the Phase Coordination Index (PCI), is significantly associated with mobility limitations in older adults, even after adjusting for other gait features. Methods: We conducted a cross-sectional analysis of performance-based measures of mobility in older adults (N = 164) 77-101 years of age, participants in the population-based MOBILIZE Boston Study. Mobility outcomes included the Short Physical Performance Battery (SPPB) and each of its three components. Multivariable linear regression models, adjusting for age and gender, were used to examine the associations of PCI and the coefficients of variation of stride length, width and time, stance time, and step width with each outcome. Results: PCI accounted for more variance in SPPB score (R2 = 0.21), gait speed (R2 = 0.17), chair rise score (R2 = 0.10), and balance score (R2 = 0.09) than any of the other gait measures. Impaired gait coordination was significantly associated with performance on the SPPB and each of its component tasks, even after accounting for gait measures previously linked to mobility tasks (all P < 0.05). In multivariable linear regression modeling PCI accounted for an additional 9% of the variance in SPPB score (P < 0.001), after accounting for the other gait variables, age, and gender. Conclusions: This study shows that impaired gait coordination is associated with poorer mobility performance in older adults, independent of other gait variables previously linked to mobility tasks.

KW - Aging

KW - Coordination

KW - Gait

KW - Mobility

UR - http://www.scopus.com/inward/record.url?scp=84964397295&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964397295&partnerID=8YFLogxK

U2 - 10.1016/j.exger.2016.04.009

DO - 10.1016/j.exger.2016.04.009

M3 - Article

C2 - 27086065

AN - SCOPUS:84964397295

VL - 80

SP - 12

EP - 16

JO - Experimental Gerontology

JF - Experimental Gerontology

SN - 0531-5565

ER -