Abstract
We report on a child with chronic granulomatous disease who at the age of 13 years was diagnosed with glioblastoma multiforme of the left thalamus. Therapy included subtotal resection, radiation to the tumor bed (60Gy), and concomitant chemotherapy with daily thalidomide (250mg/m), both during radiation and for 5 years thereafter. Currently, she is 9 years from diagnosis and has no evidence of disease. Therapy with thalidomide did not increase her infection complications and provided excellent quality of life. This is the first report of glioblastoma multiforme in a patient with chronic granulomatous disease treated with surgery, radiation, and thalidomide who is a long-term survivor.
Original language | English (US) |
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Pages (from-to) | 965-969 |
Number of pages | 5 |
Journal | Journal of Pediatric Hematology/Oncology |
Volume | 31 |
Issue number | 12 |
DOIs | |
State | Published - Dec 2009 |
Keywords
- Chronic granulomatous disease
- Glioblastoma
- Thalidomide
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology