Glioblastoma multiforme in a patient with chronic granulomatous disease treated with subtotal resection, radiation, and thalidomide: Case report of a long-term survivor

Dolly G. Aguilera, Tadanori Tomita, Veena Rajaram, Jason Fangusaro, Ben Z. Katz, Stanford Shulman, Stewart Goldman

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

We report on a child with chronic granulomatous disease who at the age of 13 years was diagnosed with glioblastoma multiforme of the left thalamus. Therapy included subtotal resection, radiation to the tumor bed (60Gy), and concomitant chemotherapy with daily thalidomide (250mg/m), both during radiation and for 5 years thereafter. Currently, she is 9 years from diagnosis and has no evidence of disease. Therapy with thalidomide did not increase her infection complications and provided excellent quality of life. This is the first report of glioblastoma multiforme in a patient with chronic granulomatous disease treated with surgery, radiation, and thalidomide who is a long-term survivor.

Original languageEnglish (US)
Pages (from-to)965-969
Number of pages5
JournalJournal of Pediatric Hematology/Oncology
Volume31
Issue number12
DOIs
StatePublished - Dec 1 2009

Keywords

  • Chronic granulomatous disease
  • Glioblastoma
  • Thalidomide

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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