Gold-catalysed synthesis of amino acid-derived 2,5-disubstituted oxazoles

Christopher L. Paradise, Pooja R. Sarkar, Mina Razzak, Jef K. De Brabander

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Amino acid-derived propargylic amides are cyclised in a one-pot, Au(iii)-catalysed operation to yield 5-bromomethyl oxazoles. These compounds are further elaborated to bis-heterocycles, dipeptide mimics and more.

Original languageEnglish (US)
Pages (from-to)4017-4020
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume9
Issue number11
DOIs
StatePublished - Jun 7 2011

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Gold-catalysed synthesis of amino acid-derived 2,5-disubstituted oxazoles'. Together they form a unique fingerprint.

  • Cite this