Guidelines for the prevention of intravascular catheter-related infections

Naomi P. O'Grady, Mary Alexander, E. Patchen Dellinger, Julie L. Gerberding, Stephen O. Heard, Dennis G. Maki, Henry Masur, Rita D. McCormick, Leonard A. Mermel, Michele L. Pearson, Issam I. Raad, Adrienne Randolph, Robert A. Weinstein, Jane D. Siegel, Raymond Y W Chinn, Alfred DeMaria, Elaine L. Larson, James T. Lee, Ramon E. Moncada, William A. RutalaWilliam E. Scheckler, Beth H. Stover, Marjorie A. Underwood

Research output: Contribution to journalArticle

414 Citations (Scopus)

Abstract

BACKGROUND: Although many catheter-related blood-stream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented. OBJECTIVE: To update an existing evidenced-based guideline that promotes strategies to prevent CRBSIs. DATA SOURCES: The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles. STUDIES INCLUDED: Laboratory-based studies, controlled clinical trials, prospective interventional trials, and epidemiologic investigations. OUTCOME MEASURES: Reduction in CRBSI, catheter colonization, or catheter-related infection. SYNTHESIS: The recommended preventive strategies with the strongest supportive evidence are education and training of healthcare providers who insert and maintain catheters; maximal sterile barrier precautions during central venous catheter insertion; use of a 2% chlorhexidine preparation for skin antisepsis; no routine replacement of central venous catheters for prevention of infection; and use of antiseptic/antibiotic-impregnated short-term central venous catheters if the rate of infection is high despite adherence to other strategies (ie, education and training, maximal sterile barrier precautions, and 2% chlorhexidine for skin antisepsis). CONCLUSION: Successful implementation of these evidence-based interventions can reduce the risk for serious catheter-related infection.

Original languageEnglish (US)
Pages (from-to)759-769
Number of pages11
JournalInfection Control and Hospital Epidemiology
Volume23
Issue number12
DOIs
StatePublished - Dec 1 2002

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Catheter-Related Infections
Guidelines
Catheters
Central Venous Catheters
Infection
Antisepsis
Chlorhexidine
Education
Skin
Local Anti-Infective Agents
Controlled Clinical Trials
Bibliography
MEDLINE
Health Personnel
Databases
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

O'Grady, N. P., Alexander, M., Dellinger, E. P., Gerberding, J. L., Heard, S. O., Maki, D. G., ... Underwood, M. A. (2002). Guidelines for the prevention of intravascular catheter-related infections. Infection Control and Hospital Epidemiology, 23(12), 759-769. https://doi.org/10.1086/502007

Guidelines for the prevention of intravascular catheter-related infections. / O'Grady, Naomi P.; Alexander, Mary; Dellinger, E. Patchen; Gerberding, Julie L.; Heard, Stephen O.; Maki, Dennis G.; Masur, Henry; McCormick, Rita D.; Mermel, Leonard A.; Pearson, Michele L.; Raad, Issam I.; Randolph, Adrienne; Weinstein, Robert A.; Siegel, Jane D.; Chinn, Raymond Y W; DeMaria, Alfred; Larson, Elaine L.; Lee, James T.; Moncada, Ramon E.; Rutala, William A.; Scheckler, William E.; Stover, Beth H.; Underwood, Marjorie A.

In: Infection Control and Hospital Epidemiology, Vol. 23, No. 12, 01.12.2002, p. 759-769.

Research output: Contribution to journalArticle

O'Grady, NP, Alexander, M, Dellinger, EP, Gerberding, JL, Heard, SO, Maki, DG, Masur, H, McCormick, RD, Mermel, LA, Pearson, ML, Raad, II, Randolph, A, Weinstein, RA, Siegel, JD, Chinn, RYW, DeMaria, A, Larson, EL, Lee, JT, Moncada, RE, Rutala, WA, Scheckler, WE, Stover, BH & Underwood, MA 2002, 'Guidelines for the prevention of intravascular catheter-related infections', Infection Control and Hospital Epidemiology, vol. 23, no. 12, pp. 759-769. https://doi.org/10.1086/502007
O'Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG et al. Guidelines for the prevention of intravascular catheter-related infections. Infection Control and Hospital Epidemiology. 2002 Dec 1;23(12):759-769. https://doi.org/10.1086/502007
O'Grady, Naomi P. ; Alexander, Mary ; Dellinger, E. Patchen ; Gerberding, Julie L. ; Heard, Stephen O. ; Maki, Dennis G. ; Masur, Henry ; McCormick, Rita D. ; Mermel, Leonard A. ; Pearson, Michele L. ; Raad, Issam I. ; Randolph, Adrienne ; Weinstein, Robert A. ; Siegel, Jane D. ; Chinn, Raymond Y W ; DeMaria, Alfred ; Larson, Elaine L. ; Lee, James T. ; Moncada, Ramon E. ; Rutala, William A. ; Scheckler, William E. ; Stover, Beth H. ; Underwood, Marjorie A. / Guidelines for the prevention of intravascular catheter-related infections. In: Infection Control and Hospital Epidemiology. 2002 ; Vol. 23, No. 12. pp. 759-769.
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AU - O'Grady, Naomi P.

AU - Alexander, Mary

AU - Dellinger, E. Patchen

AU - Gerberding, Julie L.

AU - Heard, Stephen O.

AU - Maki, Dennis G.

AU - Masur, Henry

AU - McCormick, Rita D.

AU - Mermel, Leonard A.

AU - Pearson, Michele L.

AU - Raad, Issam I.

AU - Randolph, Adrienne

AU - Weinstein, Robert A.

AU - Siegel, Jane D.

AU - Chinn, Raymond Y W

AU - DeMaria, Alfred

AU - Larson, Elaine L.

AU - Lee, James T.

AU - Moncada, Ramon E.

AU - Rutala, William A.

AU - Scheckler, William E.

AU - Stover, Beth H.

AU - Underwood, Marjorie A.

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N2 - BACKGROUND: Although many catheter-related blood-stream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented. OBJECTIVE: To update an existing evidenced-based guideline that promotes strategies to prevent CRBSIs. DATA SOURCES: The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles. STUDIES INCLUDED: Laboratory-based studies, controlled clinical trials, prospective interventional trials, and epidemiologic investigations. OUTCOME MEASURES: Reduction in CRBSI, catheter colonization, or catheter-related infection. SYNTHESIS: The recommended preventive strategies with the strongest supportive evidence are education and training of healthcare providers who insert and maintain catheters; maximal sterile barrier precautions during central venous catheter insertion; use of a 2% chlorhexidine preparation for skin antisepsis; no routine replacement of central venous catheters for prevention of infection; and use of antiseptic/antibiotic-impregnated short-term central venous catheters if the rate of infection is high despite adherence to other strategies (ie, education and training, maximal sterile barrier precautions, and 2% chlorhexidine for skin antisepsis). CONCLUSION: Successful implementation of these evidence-based interventions can reduce the risk for serious catheter-related infection.

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