Headache Caused by a Single Lesion of Multiple Sclerosis in the Periaqueductal Gray Area

D. C. Haas, P. F. Kent, Deborah I Friedman

Research output: Contribution to journalArticlepeer-review

143 Scopus citations

Abstract

SYNOPSIS We report a severe acute headache that occurred in conjunction with a solitary fresh lesion of multiple sclerosis in the periaqueductal gray region of a 16‐year‐old girl. This unique natural event supports the recent proposition, based on observations of patients with implanted electrodes, that perturbations of the periaqueductal gray region can produce headache. It also suggests that headaches accompanying attacks of multiple sclerosis are due to disturbances in particular regions of the brain.

Original languageEnglish (US)
Pages (from-to)452-454
Number of pages3
JournalHeadache: The Journal of Head and Face Pain
Volume33
Issue number8
DOIs
StatePublished - Sep 1993

Keywords

  • acute headache
  • multiple sclerosis
  • periaqueductal gray region

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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