Heart rate variability as a predictor of death in burn patients

Michael J. Loguidice, Robert C. Schutt, Jureta W. Horton, Joseph P. Minei, Ellen C. Keeley

Research output: Contribution to journalArticle

3 Scopus citations


Heart rate variability (HRV), a noninvasive technique used to quantify fluctuations in the interval between normal heart beats (NN), is a predictor of mortality in some patient groups. The aim of this study was to assess HRV in burn trauma patients as a predictor of mortality. The authors prospectively performed 24-hour Holter monitoring on burn patients and collected demographic information, burn injury details, and in-hospital clinical events. Analysis of HRV in the time and frequency domains was performed. A total of 40 burn patients with a mean age of 44 ± 15 years were enrolled. Mean %TBSA burn was 27 ± 22% for the overall population and was significantly higher in those who died compared with those who survived (55 ± 23% vs 19 ± 13%; P 2 = 0.113, 95% CI = -0.587 to -0.028, two-tailed P =.034), as well as with ultra low frequency power and %TBSA burn (r = -0.351, R2 = 0.123, 95% CI = -0.152 to -0.009; P =.027). The receiver-operator characteristic showed the area under the curve for %TBSA as a predictor of death was 0.82 (P

Original languageEnglish (US)
Pages (from-to)e227-e233
JournalJournal of Burn Care and Research
Issue number3
StatePublished - 2016


ASJC Scopus subject areas

  • Emergency Medicine
  • Rehabilitation
  • Surgery

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