Heat shock protein 108 mRNA expression during chicken retina development

Dong Hoon Shin, Hyun Joon Kim, Jaehyup Kim, Su Ryeon Bae, Sa Sun Cho

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In a developmental study on the expression of heat shock protein 108 (HSP108) mRNA in the chicken retina, we found different spatial and temporal expressions of HSP108 mRNA in each retinal layer. While intense HSP108 signals were found in the retina neuroblast layer at embryonic day 5 (E5), the ganglion cell population (GC), inner nuclear layer (IN) and pigment epithelium (PE) showed HSP108 expression at E9. At E14, HSP108 signals were reduced versus the previous stages even though signals were still detected in the GC, the IN, the outer nuclear layer and the PE. HSP108 signals were still detectable at the E21 stage, although each retinal layer showed a much differentiated morphology and diminished signal intensity. These results suggest that HSP108 expression might be developmentally regulated throughout eye organogenesis and that it plays a role in ocular development.

Original languageEnglish (US)
Pages (from-to)25-28
Number of pages4
JournalNeuroscience Letters
Volume344
Issue number1
DOIs
StatePublished - Jun 19 2003
Externally publishedYes

Fingerprint

Heat-Shock Proteins
Retina
Chickens
Messenger RNA
Ganglia
Epithelium
Organogenesis
Population

Keywords

  • Ganglion cell layer
  • Heat shock protein
  • In situ hybridization
  • Inner nuclear layer
  • Oligodendrocyte
  • Retina

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Heat shock protein 108 mRNA expression during chicken retina development. / Shin, Dong Hoon; Kim, Hyun Joon; Kim, Jaehyup; Bae, Su Ryeon; Cho, Sa Sun.

In: Neuroscience Letters, Vol. 344, No. 1, 19.06.2003, p. 25-28.

Research output: Contribution to journalArticle

Shin, Dong Hoon ; Kim, Hyun Joon ; Kim, Jaehyup ; Bae, Su Ryeon ; Cho, Sa Sun. / Heat shock protein 108 mRNA expression during chicken retina development. In: Neuroscience Letters. 2003 ; Vol. 344, No. 1. pp. 25-28.
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