Helicobacter pylori and peptic ulcer disease

Walter L. Peterson

Research output: Contribution to journalReview article

611 Scopus citations

Abstract

A GRAM-NEGATIVE, microaerophilic curved bacillus found in gastric-biopsy specimens from patients with histologie gastritis was successfully cultured in Perth, Australia, in 1982 and was soon named Campylobacter pylori1 (a name later changed to Helicobacterpylori). Little attention had been paid to previous descriptions of spiral organisms in biopsy specimens of human gastric mucosa,2 3 but it now appears that at the least the organism is responsible for most cases of gastritis not associated with another known primary cause (e.g., autoimmune gastritis or eosinophilic gastritis) and that it may also be a major factor in the pathogenesis of peptic ulcer disease. The. . .

Original languageEnglish (US)
Pages (from-to)1043-1048
Number of pages6
JournalNew England Journal of Medicine
Volume324
Issue number15
DOIs
StatePublished - Apr 11 1991

ASJC Scopus subject areas

  • Medicine(all)

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