Hemolytic transfusion reaction due to interdonor Kell incompatibility. Report of two cases and review of the literature

A. P. Reiner, M. H. Sayers

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6 Citations (Scopus)

Abstract

A 74-year-old man experienced an acute hemolytic reaction following transfusion of 4 units of red blood cells. The recipient was K negative, one of the transfused units was K positive, and another contained a previously undetected anti-K with an indirect antiglobulin titer of 512. Further investigation led to the discovery of a hemolytic transfusion reaction in a second K-negative patient who received a platelet transfusion containing 50 mL of plasma from the same donor. The clinical and serologic features of these two cases and five previously reported cases of hemolytic transfusion reaction due to interdonor Kell incompatibility are summarized.

Original languageEnglish (US)
Pages (from-to)862-864
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume114
Issue number8
StatePublished - 1990

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Platelet Transfusion
Anti-Idiotypic Antibodies
Erythrocytes
Tissue Donors
Transfusion Reaction

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

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abstract = "A 74-year-old man experienced an acute hemolytic reaction following transfusion of 4 units of red blood cells. The recipient was K negative, one of the transfused units was K positive, and another contained a previously undetected anti-K with an indirect antiglobulin titer of 512. Further investigation led to the discovery of a hemolytic transfusion reaction in a second K-negative patient who received a platelet transfusion containing 50 mL of plasma from the same donor. The clinical and serologic features of these two cases and five previously reported cases of hemolytic transfusion reaction due to interdonor Kell incompatibility are summarized.",
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