Hepatotoxicity of anticholesterol, cardiovascular, and endocrine drugs and hormonal agents

S. Lahoti, W. M. Lee

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Drugs in these categories may have effects on several organs in addition to the Liver. For example, amiodarone may produce thyroid and corneal injury apart from or in addition to the phospholipidosis seen in the liver. Oral contraceptive steroids remain a rare but important concern for developing hepatic adenomas and possibly hepatocellular carcinoma, as well as a risk factor for developing Budd-Chiari syndrome in long-term users. Among the antihyperlipidemic agents, nicotinic acid, especially the sustained release formulations, may produce severe or even fatal hepatic injury. Increasing numbers of reports of hepatotoxicity from newer beta blockers and angiotensin-converting enzyme inhibitors require ongoing vigilance in patients receiving these medications.

Original languageEnglish (US)
Pages (from-to)907-922
Number of pages16
JournalGastroenterology Clinics of North America
Volume24
Issue number4
StatePublished - Dec 1 1995

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ASJC Scopus subject areas

  • Gastroenterology

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