TY - JOUR
T1 - Heroin abuse during pregnancy
T2 - Effects on perinatal outcome and early childhood growth
AU - Little, Bertis B.
AU - Snell, Laura M.
AU - Knoll, Kraig A.
AU - Ghali, Fred E.
AU - Rosenfeld, Charles R.
AU - Gant, Norman F.
PY - 1991
Y1 - 1991
N2 - Heroin abuse during pregnancy is associated with 1) fetal growth retardation and neonatal withdrawal syndrome in infants and 2) an increased frequency of abruptio placentae, sexually transmitted diseases, and other complications in mothers. Based on the findings of several small cohort studies, postnatal growth and development of infants whose mothers were addicted to heroin during pregnancy appears to fall within normal variation. In the present study, information about use of heroin and other substances during pregnancy in relation to neonatal outcome was analyzed in 47 heroin‐abusing mothers and 80 control women and their respective infants. In addition medical record information was available for postnatal growth follow‐up of 28 (58%) of heroin‐exposed children and 22 (27.5%) of control infants. Infants born to heroin addicts in this study were significantly (P<.01) smaller at birth but exhibited no increase in the frequency of congenital anomalies compared with controls. Similar to findings of previous investigators, postnatal development of infants born to addicts was not delayed.
AB - Heroin abuse during pregnancy is associated with 1) fetal growth retardation and neonatal withdrawal syndrome in infants and 2) an increased frequency of abruptio placentae, sexually transmitted diseases, and other complications in mothers. Based on the findings of several small cohort studies, postnatal growth and development of infants whose mothers were addicted to heroin during pregnancy appears to fall within normal variation. In the present study, information about use of heroin and other substances during pregnancy in relation to neonatal outcome was analyzed in 47 heroin‐abusing mothers and 80 control women and their respective infants. In addition medical record information was available for postnatal growth follow‐up of 28 (58%) of heroin‐exposed children and 22 (27.5%) of control infants. Infants born to heroin addicts in this study were significantly (P<.01) smaller at birth but exhibited no increase in the frequency of congenital anomalies compared with controls. Similar to findings of previous investigators, postnatal development of infants born to addicts was not delayed.
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U2 - 10.1002/ajhb.1310030506
DO - 10.1002/ajhb.1310030506
M3 - Article
C2 - 28597500
AN - SCOPUS:84995232574
SN - 1042-0533
VL - 3
SP - 463
EP - 468
JO - American Journal of Human Biology
JF - American Journal of Human Biology
IS - 5
ER -