The canine pancreas takes up 50-80% of somatostatin perfused over a concentration range of 20 to 4000 pg/ml, compared to <21% of insulin or glucagon. This high uptake by acinar tissue of somatostatin, a potent inhibitor of acinar function, is compatible with a system for selective intrapancreatic control of exocrine pancreatic function via the insulo-acinar portal venous system.
|Original language||English (US)|
|Number of pages||3|
|Publication status||Published - 1982|
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism