HPV-related carcinoma of the oropharynx: challenges on small biopsy specimens

Doreen Palsgrove; Justin A. Bishop

doi:10.1016/j.jasc.2020.06.001

HPV-related carcinoma of the oropharynx: challenges on small biopsy specimens

Doreen Palsgrove, Justin A. Bishop

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Human papillomavirus (HPV)-related oropharyngeal carcinoma can morphologically mimic many processes from benign to malignant and lead pathologists to incorrectly diagnose them and/or use inappropriate diagnostic terminology. Recognition of HPV-related oropharyngeal carcinoma and its variants is critical for appropriate prognostic and therapeutic considerations in small biopsy material. Various pitfalls in diagnosing these tumors on limited biopsies are discussed herein.

Original language	English (US)
Pages (from-to)	359-368
Number of pages	10
Journal	Journal of the American Society of Cytopathology
Volume	9
Issue number	5
DOIs	https://doi.org/10.1016/j.jasc.2020.06.001
State	Published - Sep 1 2020

Keywords

HPV
Human papillomavirus
Oropharynx
Squamous cell carcinoma
p16

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1016/j.jasc.2020.06.001

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title = "HPV-related carcinoma of the oropharynx: challenges on small biopsy specimens",

abstract = "Human papillomavirus (HPV)-related oropharyngeal carcinoma can morphologically mimic many processes from benign to malignant and lead pathologists to incorrectly diagnose them and/or use inappropriate diagnostic terminology. Recognition of HPV-related oropharyngeal carcinoma and its variants is critical for appropriate prognostic and therapeutic considerations in small biopsy material. Various pitfalls in diagnosing these tumors on limited biopsies are discussed herein.",

keywords = "HPV, Human papillomavirus, Oropharynx, Squamous cell carcinoma, p16",

author = "Doreen Palsgrove and Bishop, {Justin A.}",

note = "Publisher Copyright: {\textcopyright} 2020 American Society of Cytopathology",

year = "2020",

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doi = "10.1016/j.jasc.2020.06.001",

language = "English (US)",

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T1 - HPV-related carcinoma of the oropharynx

T2 - challenges on small biopsy specimens

AU - Palsgrove, Doreen

AU - Bishop, Justin A.

PY - 2020/9/1

Y1 - 2020/9/1

N2 - Human papillomavirus (HPV)-related oropharyngeal carcinoma can morphologically mimic many processes from benign to malignant and lead pathologists to incorrectly diagnose them and/or use inappropriate diagnostic terminology. Recognition of HPV-related oropharyngeal carcinoma and its variants is critical for appropriate prognostic and therapeutic considerations in small biopsy material. Various pitfalls in diagnosing these tumors on limited biopsies are discussed herein.

AB - Human papillomavirus (HPV)-related oropharyngeal carcinoma can morphologically mimic many processes from benign to malignant and lead pathologists to incorrectly diagnose them and/or use inappropriate diagnostic terminology. Recognition of HPV-related oropharyngeal carcinoma and its variants is critical for appropriate prognostic and therapeutic considerations in small biopsy material. Various pitfalls in diagnosing these tumors on limited biopsies are discussed herein.

KW - HPV

KW - Human papillomavirus

KW - Oropharynx

KW - Squamous cell carcinoma

KW - p16

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U2 - 10.1016/j.jasc.2020.06.001

DO - 10.1016/j.jasc.2020.06.001

M3 - Review article

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AN - SCOPUS:85089195166

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JO - Journal of the American Society of Cytopathology

JF - Journal of the American Society of Cytopathology

IS - 5

ER -

HPV-related carcinoma of the oropharynx: challenges on small biopsy specimens

Abstract

Keywords

ASJC Scopus subject areas

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