Hypertension and kidney literature review 2000

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Important advances in our understanding of the mechanisms and treatment of hypertension in patients at risk for renal disease and those with overt renal disease are taking place. Thus, new data suggest that hyperfiltration may be an important antecedent to the development of kidney disease in hypertensive African-Americans. Also new studies provide evidence for differential responses of endothelial function and sympathetic nerve traffic to ACE inhibitors versus dihydropyridine calcium channel blockers in hypertensives with and without overt renal disease. Important new studies also show that in proteinuric subjects ACE inhibitor treatment is superior to non-ACE treatment at reducing proteinuria add the risk of developing ESRD in non-diabetics with renal disease. In hemodialysis patients, both systolic hypertension and hypotension predict increased mortality in hemodialysis patients. And, identification of factors important in persisting hypertension in patients on hemodialysis provide new insights into improving BP control in this population. The purpose of this review is to highlight the key elements and clinical relevance of these recent studies.

Original languageEnglish (US)
Pages (from-to)253-259
Number of pages7
JournalClinical Nephrology
Volume58
Issue number4
StatePublished - Oct 1 2002

Fingerprint

Hypertension
Kidney
Renal Dialysis
Angiotensin-Converting Enzyme Inhibitors
Calcium Channel Blockers
Kidney Diseases
Proteinuria
African Americans
Hypotension
Chronic Kidney Failure
Therapeutics
Mortality
Population
1,4-dihydropyridine

Keywords

  • Angiotensin II receptor antagonists
  • Angiotensin-converting enzyme inhibitors
  • Hemodialysis
  • Hypertension
  • Sympathetic nervous system

ASJC Scopus subject areas

  • Nephrology

Cite this

Hypertension and kidney literature review 2000. / Toto, R. D.

In: Clinical Nephrology, Vol. 58, No. 4, 01.10.2002, p. 253-259.

Research output: Contribution to journalArticle

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