Imaging technologies for cardiac fiber and heart failure: a review

Shana R. Watson, James D. Dormer, Baowei Fei

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


There has been an increasing interest in studying cardiac fibers in order to improve the current knowledge regarding the mechanical and physiological properties of the heart during heart failure (HF), particularly early HF. Having a thorough understanding of the changes in cardiac fiber orientation may provide new insight into the mechanisms behind the progression of left ventricular (LV) remodeling and HF. We conducted a systematic review on various technologies for imaging cardiac fibers and its link to HF. This review covers literature reports from 1900 to 2017. PubMed and Google Scholar databases were searched using the keywords “cardiac fiber” and “heart failure” or “myofiber” and “heart failure.” This review highlights imaging methodologies, including magnetic resonance diffusion tensor imaging (MR-DTI), ultrasound, and other imaging technologies as well as their potential applications in basic and translational research on the development and progression of HF. MR-DTI and ultrasound have been most useful and significant in evaluating cardiac fibers and HF. New imaging technologies that have the ability to measure cardiac fiber orientations and identify structural and functional information of the heart will advance basic research and clinical diagnoses of HF.

Original languageEnglish (US)
Pages (from-to)273-289
Number of pages17
JournalHeart Failure Reviews
Issue number2
StatePublished - Mar 1 2018
Externally publishedYes


  • Cardiac fiber
  • Heart failure
  • MR diffusion tensor imaging
  • Magnetic resonance imaging (MRI)
  • Medical imaging
  • Myofiber
  • Ultrasound imaging

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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