Immunotherapy in Breast Cancer: the New Frontier

Zishuo I. Hu, Heather L. McArthur

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

Purpose of review: This review summarizes current immunotherapies in breast cancer, with an emphasis on immune checkpoint inhibitors and vaccines. Recent findings: Combination immunotherapy with checkpoint inhibitors and cytotoxic therapies have shown promising results. Active clinical trials are ongoing in both early stage and metastatic settings for triple negative, HER2+, and hormone-positive breast cancer patients. Summary: Ongoing challenges remain in defining biomarkers that predict response to immunotherapy, determining the optimal combination immunotherapies, and enhancing the immunogenicity of breast cancer subtypes.

Original languageEnglish (US)
Pages (from-to)35-40
Number of pages6
JournalCurrent Breast Cancer Reports
Volume10
Issue number2
DOIs
StatePublished - Jun 1 2018
Externally publishedYes

Keywords

  • Breast cancer
  • Checkpoint inhibitors
  • Immunotherapy
  • Vaccines

ASJC Scopus subject areas

  • Oncology

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