Impact of colonization pressure and strain type on methicillin-resistant staphylococcus aureus transmission in children

Victor O. Popoola, Karen C. Carroll, Tracy Ross, Nicholas G. Reich, Trish M. Perl, Aaron M. Milstone

Research output: Contribution to journalArticle

20 Scopus citations


We studied the transmissibility of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and healthcare-associated methicillin-resistant S. aureus (HA-MRSA) strains and the association of MRSA colonization pressure and MRSA transmission in critically ill children. Importantly, we found that in hospitalized children MRSA colonization pressure above 10% increases the risk of MRSA transmission 3-fold, and CA-MRSA and HA-MRSA strains have similar transmission dynamics.

Original languageEnglish (US)
Pages (from-to)1458-1460
Number of pages3
JournalClinical Infectious Diseases
Issue number10
Publication statusPublished - Nov 15 2013



  • Colonization pressure
  • Healthcare-associated infections
  • Intensive care unit
  • Methicillin-resistant Staphylococcus aureus
  • Transmission

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

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