Impact of ethnicity in upper gastrointestinal hemorrhage

Casey S. Wollenman, Rebecca Chason, Joan S. Reisch, Don C. Rockey

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

GOALS:: To examine ethnicity's role in the etiology and outcome of upper gastrointestinal hemorrhage (UGIH). BACKGROUND:: UGIH is a serious condition with considerable associated morbidity and mortality. MATERIALS AND METHODS:: We analyzed 2196 patients admitted with acute UGIH between January 2006 and February 2012. Complete clinical data were gathered prospectively and entered into our GI Bleed Registry, which captures demographic and clinical variables. Results were analyzed using the χ analyses and the analysis of variance techniques with Tukey multiple comparisons. RESULTS:: Among 2196 patients, 620 (28%) were black, 625 (29%) white, 881 (40%) Hispanic, and 70 (3%) were members of other ethnicities. Gastroduodenal ulcers (25%), esophageal varices (25%), and esophagitis (12%) were the most frequently identified causes of UGIH. Blacks experienced a high rate of gastroduodenal ulcers (199/620), whereas Hispanics most commonly had esophageal varices. In all ethnicities, the most common cause of bleeding in patients younger than 35 or older than 65 years was gastroduodenal ulcer disease. However, among patients aged 35 to 64 years, there were differences in the etiology of UGIH. Blacks aged 50 to 64 years frequently experienced gastroduodenal ulcers, whereas Hispanics aged 35 to 49 years typically had esophageal varices. Rebleeding rates were significantly lower in whites (5.8%) than in Hispanics (9.9%) or blacks (8.7%) (P=0.02). CONCLUSIONS:: By examining a diverse population, we conclude that UGIH may follow trends. Hispanics were likely to have esophageal varices and higher rebleeding rates, whereas blacks were likely to have ulcers and the highest mortality. Whites were equally likely to have ulcers or varices, but a lower rate of rebleeding.

Original languageEnglish (US)
Pages (from-to)343-350
Number of pages8
JournalJournal of Clinical Gastroenterology
Volume48
Issue number4
DOIs
StatePublished - 2014

Fingerprint

Gastrointestinal Hemorrhage
Hispanic Americans
Esophageal and Gastric Varices
Peptic Ulcer
Ulcer
Esophagitis
Mortality
Varicose Veins
Registries
Analysis of Variance
Demography
Hemorrhage
Morbidity
Population

Keywords

  • bleeding
  • demographics
  • mortality
  • peptic ulcer
  • varices

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Impact of ethnicity in upper gastrointestinal hemorrhage. / Wollenman, Casey S.; Chason, Rebecca; Reisch, Joan S.; Rockey, Don C.

In: Journal of Clinical Gastroenterology, Vol. 48, No. 4, 2014, p. 343-350.

Research output: Contribution to journalArticle

Wollenman, Casey S. ; Chason, Rebecca ; Reisch, Joan S. ; Rockey, Don C. / Impact of ethnicity in upper gastrointestinal hemorrhage. In: Journal of Clinical Gastroenterology. 2014 ; Vol. 48, No. 4. pp. 343-350.
@article{cc69b95273d34597aa442b134ac794fa,
title = "Impact of ethnicity in upper gastrointestinal hemorrhage",
abstract = "GOALS:: To examine ethnicity's role in the etiology and outcome of upper gastrointestinal hemorrhage (UGIH). BACKGROUND:: UGIH is a serious condition with considerable associated morbidity and mortality. MATERIALS AND METHODS:: We analyzed 2196 patients admitted with acute UGIH between January 2006 and February 2012. Complete clinical data were gathered prospectively and entered into our GI Bleed Registry, which captures demographic and clinical variables. Results were analyzed using the χ analyses and the analysis of variance techniques with Tukey multiple comparisons. RESULTS:: Among 2196 patients, 620 (28{\%}) were black, 625 (29{\%}) white, 881 (40{\%}) Hispanic, and 70 (3{\%}) were members of other ethnicities. Gastroduodenal ulcers (25{\%}), esophageal varices (25{\%}), and esophagitis (12{\%}) were the most frequently identified causes of UGIH. Blacks experienced a high rate of gastroduodenal ulcers (199/620), whereas Hispanics most commonly had esophageal varices. In all ethnicities, the most common cause of bleeding in patients younger than 35 or older than 65 years was gastroduodenal ulcer disease. However, among patients aged 35 to 64 years, there were differences in the etiology of UGIH. Blacks aged 50 to 64 years frequently experienced gastroduodenal ulcers, whereas Hispanics aged 35 to 49 years typically had esophageal varices. Rebleeding rates were significantly lower in whites (5.8{\%}) than in Hispanics (9.9{\%}) or blacks (8.7{\%}) (P=0.02). CONCLUSIONS:: By examining a diverse population, we conclude that UGIH may follow trends. Hispanics were likely to have esophageal varices and higher rebleeding rates, whereas blacks were likely to have ulcers and the highest mortality. Whites were equally likely to have ulcers or varices, but a lower rate of rebleeding.",
keywords = "bleeding, demographics, mortality, peptic ulcer, varices",
author = "Wollenman, {Casey S.} and Rebecca Chason and Reisch, {Joan S.} and Rockey, {Don C.}",
year = "2014",
doi = "10.1097/MCG.0000000000000025",
language = "English (US)",
volume = "48",
pages = "343--350",
journal = "Journal of Clinical Gastroenterology",
issn = "0192-0790",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Impact of ethnicity in upper gastrointestinal hemorrhage

AU - Wollenman, Casey S.

AU - Chason, Rebecca

AU - Reisch, Joan S.

AU - Rockey, Don C.

PY - 2014

Y1 - 2014

N2 - GOALS:: To examine ethnicity's role in the etiology and outcome of upper gastrointestinal hemorrhage (UGIH). BACKGROUND:: UGIH is a serious condition with considerable associated morbidity and mortality. MATERIALS AND METHODS:: We analyzed 2196 patients admitted with acute UGIH between January 2006 and February 2012. Complete clinical data were gathered prospectively and entered into our GI Bleed Registry, which captures demographic and clinical variables. Results were analyzed using the χ analyses and the analysis of variance techniques with Tukey multiple comparisons. RESULTS:: Among 2196 patients, 620 (28%) were black, 625 (29%) white, 881 (40%) Hispanic, and 70 (3%) were members of other ethnicities. Gastroduodenal ulcers (25%), esophageal varices (25%), and esophagitis (12%) were the most frequently identified causes of UGIH. Blacks experienced a high rate of gastroduodenal ulcers (199/620), whereas Hispanics most commonly had esophageal varices. In all ethnicities, the most common cause of bleeding in patients younger than 35 or older than 65 years was gastroduodenal ulcer disease. However, among patients aged 35 to 64 years, there were differences in the etiology of UGIH. Blacks aged 50 to 64 years frequently experienced gastroduodenal ulcers, whereas Hispanics aged 35 to 49 years typically had esophageal varices. Rebleeding rates were significantly lower in whites (5.8%) than in Hispanics (9.9%) or blacks (8.7%) (P=0.02). CONCLUSIONS:: By examining a diverse population, we conclude that UGIH may follow trends. Hispanics were likely to have esophageal varices and higher rebleeding rates, whereas blacks were likely to have ulcers and the highest mortality. Whites were equally likely to have ulcers or varices, but a lower rate of rebleeding.

AB - GOALS:: To examine ethnicity's role in the etiology and outcome of upper gastrointestinal hemorrhage (UGIH). BACKGROUND:: UGIH is a serious condition with considerable associated morbidity and mortality. MATERIALS AND METHODS:: We analyzed 2196 patients admitted with acute UGIH between January 2006 and February 2012. Complete clinical data were gathered prospectively and entered into our GI Bleed Registry, which captures demographic and clinical variables. Results were analyzed using the χ analyses and the analysis of variance techniques with Tukey multiple comparisons. RESULTS:: Among 2196 patients, 620 (28%) were black, 625 (29%) white, 881 (40%) Hispanic, and 70 (3%) were members of other ethnicities. Gastroduodenal ulcers (25%), esophageal varices (25%), and esophagitis (12%) were the most frequently identified causes of UGIH. Blacks experienced a high rate of gastroduodenal ulcers (199/620), whereas Hispanics most commonly had esophageal varices. In all ethnicities, the most common cause of bleeding in patients younger than 35 or older than 65 years was gastroduodenal ulcer disease. However, among patients aged 35 to 64 years, there were differences in the etiology of UGIH. Blacks aged 50 to 64 years frequently experienced gastroduodenal ulcers, whereas Hispanics aged 35 to 49 years typically had esophageal varices. Rebleeding rates were significantly lower in whites (5.8%) than in Hispanics (9.9%) or blacks (8.7%) (P=0.02). CONCLUSIONS:: By examining a diverse population, we conclude that UGIH may follow trends. Hispanics were likely to have esophageal varices and higher rebleeding rates, whereas blacks were likely to have ulcers and the highest mortality. Whites were equally likely to have ulcers or varices, but a lower rate of rebleeding.

KW - bleeding

KW - demographics

KW - mortality

KW - peptic ulcer

KW - varices

UR - http://www.scopus.com/inward/record.url?scp=84896314436&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84896314436&partnerID=8YFLogxK

U2 - 10.1097/MCG.0000000000000025

DO - 10.1097/MCG.0000000000000025

M3 - Article

C2 - 24275716

AN - SCOPUS:84896314436

VL - 48

SP - 343

EP - 350

JO - Journal of Clinical Gastroenterology

JF - Journal of Clinical Gastroenterology

SN - 0192-0790

IS - 4

ER -