Incorporating endorectal MR elastography into multi-parametric MRI for prostate cancer imaging: Initial feasibility in volunteers

Arvin Arani, Michael Da Rosa, Elizabeth Ramsay, Don B. Plewes, Masoom A. Haider, Rajiv Chopra

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Purpose To investigate the tolerability and technical feasibility of performing endorectal MR elastography (eMRE) in human volunteers within the representative age group commonly affected by prostate cancer. Materials and Methods Endorectal MRE was conducted on seven volunteers in a 1.5 Tesla (T) MR imager using a rigid endorectal coil. Another five volunteers were imaged on a 3T MR imager using an inflatable balloon type endorectal coil. Tolerability was accessed for vibration amplitudes of ±1-50 μm and for frequencies of 100-300 Hz. Results All 12 volunteers tolerated the displacements necessary to successfully perform eMRE. Shear waves with frequencies up to 300 Hz could propagate across the entire prostate using both coil designs. Conclusion The results of this study motivate further investigation of eMRE in prostate cancer patients to help determine if there is an added value of integrating eMRE into existing multi-parametric prostate MRI exams. J. Magn. Reson. Imaging 2013;38:1251-1260. © 2013 Wiley Periodicals, Inc.

Original languageEnglish (US)
Pages (from-to)1251-1260
Number of pages10
JournalJournal of Magnetic Resonance Imaging
Volume38
Issue number5
DOIs
StatePublished - Nov 1 2013

    Fingerprint

Keywords

  • MR elastography
  • cancer
  • endorectal
  • prostate imaging
  • prostate stiffness
  • tissue stiffness

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this