Increase in invasive streptococcus pneumoniae infections in children with sickle cell disease since pneumococcal conjugate vaccine licensure

Timothy L. McCavit, Charles T. Quinn, Chonnamet Techasaensiri, Zora R. Rogers

Research output: Contribution to journalArticle

49 Scopus citations

Abstract

Invasive pneumococcal disease (IPD) in children with sickle cell disease has decreased with prophylactic penicillin, pneumococcal polysaccharide vaccine, and pneumococcal protein-conjugate vaccine usage. We report 10 IPD cases since pneumococcal protein-conjugate vaccine licensure, including a recent surge of non-vaccine serotypes. IPD continues to be a serious risk in sickle cell disease.

Original languageEnglish (US)
Pages (from-to)505-507
Number of pages3
JournalJournal of Pediatrics
Volume158
Issue number3
DOIs
StatePublished - Mar 1 2011

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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