Inhibition of Angiotensin-Converting Enzyme in Congestive Heart Failure

Harry Feld, Mark A. Greenberg, Marvin E. Jaffe, Robert A. Hamilton, Milton Packer, Wai Hung Lee

Research output: Contribution to journalLetter

4 Citations (Scopus)

Abstract

To the Editor: The recent study by Packer et al. (Oct. 2 issue),1 comparing the effects of enalapril and captopril in heart failure, has problems with study design that make the implications of the study less broad than the investigators intended. The dosages of the inhibitors of angiotensin-converting enzyme (150 mg of captopril per day and 40 mg of enalapril per day) are larger than those currently used by most clinicians. Captopril was originally investigated in doses of up to 150 mg three times a day. However, the tendency over recent years has been to use this drug in doses…

Original languageEnglish (US)
Pages (from-to)879-880
Number of pages2
JournalNew England Journal of Medicine
Volume316
Issue number14
DOIs
StatePublished - Apr 2 1987

Fingerprint

Captopril
Peptidyl-Dipeptidase A
Enalapril
Heart Failure
Angiotensin-Converting Enzyme Inhibitors
Research Personnel
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Feld, H., Greenberg, M. A., Jaffe, M. E., Hamilton, R. A., Packer, M., & Lee, W. H. (1987). Inhibition of Angiotensin-Converting Enzyme in Congestive Heart Failure. New England Journal of Medicine, 316(14), 879-880. https://doi.org/10.1056/NEJM198704023161414

Inhibition of Angiotensin-Converting Enzyme in Congestive Heart Failure. / Feld, Harry; Greenberg, Mark A.; Jaffe, Marvin E.; Hamilton, Robert A.; Packer, Milton; Lee, Wai Hung.

In: New England Journal of Medicine, Vol. 316, No. 14, 02.04.1987, p. 879-880.

Research output: Contribution to journalLetter

Feld, H, Greenberg, MA, Jaffe, ME, Hamilton, RA, Packer, M & Lee, WH 1987, 'Inhibition of Angiotensin-Converting Enzyme in Congestive Heart Failure', New England Journal of Medicine, vol. 316, no. 14, pp. 879-880. https://doi.org/10.1056/NEJM198704023161414
Feld, Harry ; Greenberg, Mark A. ; Jaffe, Marvin E. ; Hamilton, Robert A. ; Packer, Milton ; Lee, Wai Hung. / Inhibition of Angiotensin-Converting Enzyme in Congestive Heart Failure. In: New England Journal of Medicine. 1987 ; Vol. 316, No. 14. pp. 879-880.
@article{25aea9f0a9324ae4856ce2e1690e09af,
title = "Inhibition of Angiotensin-Converting Enzyme in Congestive Heart Failure",
abstract = "To the Editor: The recent study by Packer et al. (Oct. 2 issue),1 comparing the effects of enalapril and captopril in heart failure, has problems with study design that make the implications of the study less broad than the investigators intended. The dosages of the inhibitors of angiotensin-converting enzyme (150 mg of captopril per day and 40 mg of enalapril per day) are larger than those currently used by most clinicians. Captopril was originally investigated in doses of up to 150 mg three times a day. However, the tendency over recent years has been to use this drug in doses…",
author = "Harry Feld and Greenberg, {Mark A.} and Jaffe, {Marvin E.} and Hamilton, {Robert A.} and Milton Packer and Lee, {Wai Hung}",
year = "1987",
month = "4",
day = "2",
doi = "10.1056/NEJM198704023161414",
language = "English (US)",
volume = "316",
pages = "879--880",
journal = "New England Journal of Medicine",
issn = "0028-4793",
publisher = "Massachussetts Medical Society",
number = "14",

}

TY - JOUR

T1 - Inhibition of Angiotensin-Converting Enzyme in Congestive Heart Failure

AU - Feld, Harry

AU - Greenberg, Mark A.

AU - Jaffe, Marvin E.

AU - Hamilton, Robert A.

AU - Packer, Milton

AU - Lee, Wai Hung

PY - 1987/4/2

Y1 - 1987/4/2

N2 - To the Editor: The recent study by Packer et al. (Oct. 2 issue),1 comparing the effects of enalapril and captopril in heart failure, has problems with study design that make the implications of the study less broad than the investigators intended. The dosages of the inhibitors of angiotensin-converting enzyme (150 mg of captopril per day and 40 mg of enalapril per day) are larger than those currently used by most clinicians. Captopril was originally investigated in doses of up to 150 mg three times a day. However, the tendency over recent years has been to use this drug in doses…

AB - To the Editor: The recent study by Packer et al. (Oct. 2 issue),1 comparing the effects of enalapril and captopril in heart failure, has problems with study design that make the implications of the study less broad than the investigators intended. The dosages of the inhibitors of angiotensin-converting enzyme (150 mg of captopril per day and 40 mg of enalapril per day) are larger than those currently used by most clinicians. Captopril was originally investigated in doses of up to 150 mg three times a day. However, the tendency over recent years has been to use this drug in doses…

UR - http://www.scopus.com/inward/record.url?scp=0023101934&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023101934&partnerID=8YFLogxK

U2 - 10.1056/NEJM198704023161414

DO - 10.1056/NEJM198704023161414

M3 - Letter

C2 - 3029591

AN - SCOPUS:0023101934

VL - 316

SP - 879

EP - 880

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 14

ER -