Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte

Medicine & Life Sciences

• SCH 58053 100%
• ATP-Binding Cassette Transporters 47%
• Enterocytes 47%
• Adenosine Triphosphate 31%
• Cholesterol 29%
• Messenger RNA 22%
• Ezetimibe 13%
• 1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone 11%
• Sterols 11%
• Bile Acids and Salts 10%
• 129 Strain Mouse 7%
• Anticholesteremic Agents 7%
• Dietary Cholesterol 7%
• Intestinal Absorption 5%
• Microvilli 5%
• Jejunum 5%
• Liver 5%
• LDL Cholesterol 4%
• Rodentia 4%
• Diet 3%
• Lipids 3%
• Membranes 2%
• Animals 2%
• Proteins 1%

Chemical Compounds

• Adenosine 38%
• Cholesterol 35%
• Bile Acid 9%
• Sterol 8%
• Ezetimibe 6%
• Low-Density Lipoprotein Cholesterol 6%
• Pharmacological Metabolism 3%
• Lipid 2%
• Plasma 2%
• Protein 1%