Intense leuco-erythroblastic blood picture resembling erythro-leukaemia in sickle cell disease

a case report.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Florid leuco-erythroblastic blood picture in sickle cell disease (SCD) resembling chronic myeloid leukaemia and secondary dyserythropoietic activity resembling Di Guglielmo's disease in SCD have previously been reported. The aim of this study is to further focus attention on this phenomenon and to report that megaloblastic crisis in SCD can be misdiagnosed as acute leukaemia (erythroleukaemia). The need to do haemoglobin electrophoresis in all suspected cases of acute or chronic leukaemia in people of African ancestry is advocated.

Original languageEnglish (US)
Pages (from-to)419-421
Number of pages3
JournalEast African Medical Journal
Volume66
Issue number6
StatePublished - Jun 1989

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Sickle Cell Anemia
Leukemia
Blood
Leukemia, Erythroblastic, Acute
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Diagnostic Errors
Electrophoresis
Hemoglobins

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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title = "Intense leuco-erythroblastic blood picture resembling erythro-leukaemia in sickle cell disease: a case report.",
abstract = "Florid leuco-erythroblastic blood picture in sickle cell disease (SCD) resembling chronic myeloid leukaemia and secondary dyserythropoietic activity resembling Di Guglielmo's disease in SCD have previously been reported. The aim of this study is to further focus attention on this phenomenon and to report that megaloblastic crisis in SCD can be misdiagnosed as acute leukaemia (erythroleukaemia). The need to do haemoglobin electrophoresis in all suspected cases of acute or chronic leukaemia in people of African ancestry is advocated.",
author = "Adedeji, {M. O.}",
year = "1989",
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pages = "419--421",
journal = "East African Medical Journal",
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N2 - Florid leuco-erythroblastic blood picture in sickle cell disease (SCD) resembling chronic myeloid leukaemia and secondary dyserythropoietic activity resembling Di Guglielmo's disease in SCD have previously been reported. The aim of this study is to further focus attention on this phenomenon and to report that megaloblastic crisis in SCD can be misdiagnosed as acute leukaemia (erythroleukaemia). The need to do haemoglobin electrophoresis in all suspected cases of acute or chronic leukaemia in people of African ancestry is advocated.

AB - Florid leuco-erythroblastic blood picture in sickle cell disease (SCD) resembling chronic myeloid leukaemia and secondary dyserythropoietic activity resembling Di Guglielmo's disease in SCD have previously been reported. The aim of this study is to further focus attention on this phenomenon and to report that megaloblastic crisis in SCD can be misdiagnosed as acute leukaemia (erythroleukaemia). The need to do haemoglobin electrophoresis in all suspected cases of acute or chronic leukaemia in people of African ancestry is advocated.

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