Intracranial aneurysm and vasculopathy after surgery and radiation therapy for craniopharyngioma: Case report

Paulo Pereira, Antonio Cerejo, Joaquim Cruz, Rui Vaz, João Lobo Antunes, H. Hunt Batjer, Armando Basso

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

OBJECTIVE AND IMPORTANCE: This case report illustrates the possible occurrence of intracranial aneurysms after surgery and radiation-induced vasculopathy. CLINICAL PRESENTATION: An internal carotid bifurcation aneurysm was diagnosed in a 19-year-old woman in a routine follow-up examination by magnetic resonance imaging 5 years after subtotal removal of a giant cystic craniopharyngioma treated by postoperative external radiotherapy. The presence of the aneurysm was confirmed by angiography. INTERVENTION: It was decided to treat the aneurysm by embolization with Guglielmi detachable coiling. However, at the beginning of the procedure, a few weeks after the diagnosis, a dramatic reduction in the carotid artery blood flow was observed, along with signs of thrombosis inside the aneurysm. In light of these findings, the procedure was aborted. Four months later, another angiographic examination confirmed the exclusion of the aneurysm and compensatory flow through the external carotid artery. CONCLUSION: During the assessment of patients who have undergone postoperative radiotherapy, the potential for the development of aneurysms and radiation-induced vasculopathy exists and should be kept in mind. Considering the potential for spontaneous thrombosis of these aneurysms, cautious judgment is recommended before making a decision to treat them.

Original languageEnglish (US)
Pages (from-to)885-888
Number of pages4
JournalNeurosurgery
Volume50
Issue number4
DOIs
StatePublished - Apr 1 2002

Fingerprint

Craniopharyngioma
Intracranial Aneurysm
Aneurysm
Radiotherapy
Thrombosis
Radiation
External Carotid Artery
Carotid Arteries
Decision Making
Angiography
Magnetic Resonance Imaging

Keywords

  • Aneurysm
  • Cerebral vasculopathy
  • Craniopharyngioma
  • Radiation therapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Intracranial aneurysm and vasculopathy after surgery and radiation therapy for craniopharyngioma : Case report. / Pereira, Paulo; Cerejo, Antonio; Cruz, Joaquim; Vaz, Rui; Lobo Antunes, João; Hunt Batjer, H.; Basso, Armando.

In: Neurosurgery, Vol. 50, No. 4, 01.04.2002, p. 885-888.

Research output: Contribution to journalArticle

Pereira, Paulo ; Cerejo, Antonio ; Cruz, Joaquim ; Vaz, Rui ; Lobo Antunes, João ; Hunt Batjer, H. ; Basso, Armando. / Intracranial aneurysm and vasculopathy after surgery and radiation therapy for craniopharyngioma : Case report. In: Neurosurgery. 2002 ; Vol. 50, No. 4. pp. 885-888.
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