Intravascular use of isobutyl 2-cyanoacrylate

Part 1. Treatment of intracranial arteriovenous malformations

D. Samson, Q. M. Ditmore, C. W. Beyer

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

The intravascular use of the rapidly polymerizing acrylic compound, isobutyl 2-cyanoacrylate (IBC), in 10 patients with intracranial arteriovenous malformations (AVMs) is described. The monomer was introduced into each malformation at craniotomy using angiographic control and microvascular dissection technique to identify, isolate, and inject the major components of each vascular lesion while attempting to preserve normal arterial circulation. Postoperative angiography was used routinely to evaluate the results of IBC embolization. Four patients underwent the injection and immediate surgical excision of an intracranial AVM, and 6 underwent injection alone; 3 of the latter had residual malformation demonstrated on postoperative angiography, and 1 of these patients had the remnants of her malformation occluded by a second embolic procedure. There was no operative mortality nor permanent neurological morbidity. Three patients suffered transient neurological dysfunction in the immediate postoperative period.

Original languageEnglish (US)
Pages (from-to)43-51
Number of pages9
JournalNeurosurgery
Volume8
Issue number1
StatePublished - 1981

Fingerprint

Bucrylate
Intracranial Arteriovenous Malformations
Angiography
Injections
Craniotomy
Therapeutics
Postoperative Period
Blood Vessels
Dissection
Morbidity
Mortality

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Intravascular use of isobutyl 2-cyanoacrylate : Part 1. Treatment of intracranial arteriovenous malformations. / Samson, D.; Ditmore, Q. M.; Beyer, C. W.

In: Neurosurgery, Vol. 8, No. 1, 1981, p. 43-51.

Research output: Contribution to journalArticle

Samson, D. ; Ditmore, Q. M. ; Beyer, C. W. / Intravascular use of isobutyl 2-cyanoacrylate : Part 1. Treatment of intracranial arteriovenous malformations. In: Neurosurgery. 1981 ; Vol. 8, No. 1. pp. 43-51.
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