Intravascular use of isobutyl 2-cyanoacrylate: Part 1. Treatment of intracranial arteriovenous malformations

D. Samson, Q. M. Ditmore, C. W. Beyer

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

The intravascular use of the rapidly polymerizing acrylic compound, isobutyl 2-cyanoacrylate (IBC), in 10 patients with intracranial arteriovenous malformations (AVMs) is described. The monomer was introduced into each malformation at craniotomy using angiographic control and microvascular dissection technique to identify, isolate, and inject the major components of each vascular lesion while attempting to preserve normal arterial circulation. Postoperative angiography was used routinely to evaluate the results of IBC embolization. Four patients underwent the injection and immediate surgical excision of an intracranial AVM, and 6 underwent injection alone; 3 of the latter had residual malformation demonstrated on postoperative angiography, and 1 of these patients had the remnants of her malformation occluded by a second embolic procedure. There was no operative mortality nor permanent neurological morbidity. Three patients suffered transient neurological dysfunction in the immediate postoperative period.

Original languageEnglish (US)
Pages (from-to)43-51
Number of pages9
JournalNeurosurgery
Volume8
Issue number1
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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