Invasive Group C Streptococcus infection associated with rhabdomyolysis and disseminated intravascular coagulation in a previously healthy adult

I. C. Ojukwu, D. W. Newton, A. E. Luque, M. Y S Kotb, M. Menegus

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Infections with Group C Streptococci can lead to severe disease, particularly in individuals with underlying illnesses such as cardiovascular disease, malignancy or immunosuppression. We report the first case of rhabdomyolysis and disseminated intravascular coagulation secondary to Group C Streptococcus in a previous healthy male. A toxic shock-like syndrome associated with Group C and Group G Streptococci has been reported. However, unlike with Group A Streptococci, production of endotoxins by these organisms is less well defined. We tested the patient's isolate for its ability to produce superantigenic toxins and to induce a mitogenic response. Although it is not known whether Group C Streptococci require special growth conditions for the production of superantigens, we could not demonstrate either the production of exotoxins or the induction of a mitogenic response.

Original languageEnglish (US)
Pages (from-to)227-229
Number of pages3
JournalScandinavian Journal of Infectious Diseases
Volume33
Issue number3
DOIs
StatePublished - Apr 11 2001

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Rhabdomyolysis
Disseminated Intravascular Coagulation
Streptococcus
Infection
Exotoxins
Superantigens
Septic Shock
Endotoxins
Immunosuppression
Cardiovascular Diseases
Growth
Neoplasms

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Invasive Group C Streptococcus infection associated with rhabdomyolysis and disseminated intravascular coagulation in a previously healthy adult. / Ojukwu, I. C.; Newton, D. W.; Luque, A. E.; Kotb, M. Y S; Menegus, M.

In: Scandinavian Journal of Infectious Diseases, Vol. 33, No. 3, 11.04.2001, p. 227-229.

Research output: Contribution to journalArticle

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