Involvement of the gastrointestinal tract by metastases from germ cell tumors of the testis

John W. Sweetenham, J. Michael Whitehouse, Christopher J. Williams, Graham M. Mead

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Six cases of metastatic germ cell tumors of the testis involving the gastrointestinal (GI) tract are reported. Three cases were primary seminomas, and three were nonseminomatous. All six cases involved the upper GI tract, three occurring at presentation and three at relapse, with a disease‐free interval of 3 months to 10 years. Isolated GI involvement did not occur. The presumed mode of spread was by haematogenous dissemination in three and direct extension from paraaortic lymph nodes in three. Symptoms suggestive of involvement were severe abdominal pain secondary to high intestinal obstruction or mucosal ulceration, severe lumbar pain, and symptoms of anemia as a result of clinically evident or occult blood loss. Four patients were now disease‐free after chemotherapy, one died of an unrelated illness, and one patient was receiving treatment for relapsing disease.

Original languageEnglish (US)
Pages (from-to)2566-2570
Number of pages5
JournalCancer
Volume61
Issue number12
DOIs
StatePublished - Jun 15 1988

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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