Involvement of the ileocaecal region by non-hodgkin's lymphoma in adults: Clinical features and results of treatment

J. W. Sweetenham, G. M. Mead, D. H. Wright, J. J. McKendrick, D. H. Jones, C. J. Williams, J. M.A. Whitehouse

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Between January 1977 and January 1988, 19 patients with non-Hodgkin's lymphoma (NHL) involving the ileocaecal region were cared for by the CRC Wessex Medical Oncology Unit. Fifteen of these patients had primary ileocaecal NHL (stages IE or IIE) and four had secondary involvement of this region (stage IV). The commonest clinical presentation was with abdominal pain and a palpable mass in the right iliac fossa. Bulky (>10cm) disease was a particularly common feature, and complete surgical removal was possible in only seven patients. All patients had intermediate (18) or high grade (one) NHL using the Working Formulation. The commonest histological subtype was diffuse large cell. Seventeen patients received postoperative therapy, comprising local radiotherapy in one and combination chemotherapy in the remaining 16. Eleven of the 19 patients remain disease-free 6-60 months from diagnosis. Because of the high incidence of bulky disease at this site, postoperative therapy may be indicated, even for patients with apparently completely excised stage I disease.

Original languageEnglish (US)
Pages (from-to)366-369
Number of pages4
JournalBritish Journal of Cancer
Volume60
Issue number3
DOIs
StatePublished - Sep 1989
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Sweetenham, J. W., Mead, G. M., Wright, D. H., McKendrick, J. J., Jones, D. H., Williams, C. J., & Whitehouse, J. M. A. (1989). Involvement of the ileocaecal region by non-hodgkin's lymphoma in adults: Clinical features and results of treatment. British Journal of Cancer, 60(3), 366-369. https://doi.org/10.1038/bjc.1989.286