Ipsilateral and contralateral projections to the trochlear nucleus arise from different subdivisions in the vestibular nuclei

Amy R. Coffey, Golda Anne Kevetter

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Vestibular neurons that project to the trochlear nucleus were studied following unilateral injections of horseradish peroxidase. After 48 h, the animals were perfused, transverse sections were cut, and reacted with diaminobenzidine. After injections centered on the trochlear nucleus, one-third of the labeled neurons were located in the ipsilateral superior (S) vestibular nucleus and almost half were in the contralateral medial (M) vestibular nucleus. Labeled fibers were restricted to the medial longitudinal fasciculus ipsilateral to the injection. This study supports hypotheses, based on physiological data of two vertical vestibulo-ocular pathways; one originating in the ipsilateral S that may be inhibitory and the second originating predominantly from the contralateral M that may be excitatory.

Original languageEnglish (US)
Pages (from-to)274-280
Number of pages7
JournalNeuroscience Letters
Volume99
Issue number3
DOIs
StatePublished - May 8 1989

Keywords

  • Oculomotor
  • Trochlear nerve
  • Vestibular
  • Vestibulo-ocular response

ASJC Scopus subject areas

  • Neuroscience(all)

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