Is immediate reconstruction of the mandible with nonvascularized bone graft following resection of benign pathology a viable treatment option?

Thomas Schlieve, William Hull, Michael Miloro, Antonia Kolokythas

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose The purpose of this study was to address the following clinical question: Is immediate reconstruction of the mandible with a nonvascularized bone graft after resection of benign pathology a viable treatment option? Another purpose was to determine whether any variables affect the success of this treatment approach. Materials and Methods The authors implemented a retrospective cohort study from a sample of patients diagnosed with a benign tumor of the mandible who were treated with segmental resection and primary reconstruction with an autogenous nonvascularized bone graft. The predictor variables were age, gender, lesion size, and diagnosis, and the outcome variable was graft success determined by re-establishment of mandibular continuity with sufficient bone for implant placement. The χ2 test was used for statistical analysis of the categorical data and P values less than.05 were considered statistically significant. Results Twenty patients with benign mandibular tumors were treated with transoral resection and immediate reconstruction with nonvascularized bone grafts. The mean age was 28.3 years (range, 9 to 63 yr) and 55% (11 of 20) were men. The most common lesion type was ameloblastoma (13 of 20) and all patients underwent reconstruction with autogenous anterior iliac crest bone grafting. Ninety percent of patients (18 of 20) had successful reconstruction. Ten patients underwent successful implant placement and restoration. Conclusions Using careful patient selection, treatment of benign pathology with transoral resection and immediate reconstruction with a nonvascularized bone graft from the anterior iliac crest can be successful. In addition, the total treatment time from implant restoration to return to preoperative function is minimized. Therefore, this method of treatment is a viable treatment option and an alternative to delayed reconstruction or reconstruction with vascularized bone flaps.

Original languageEnglish (US)
Pages (from-to)541-549
Number of pages9
JournalJournal of Oral and Maxillofacial Surgery
Volume73
Issue number3
DOIs
StatePublished - Jan 1 2015

Fingerprint

Mandible
Pathology
Transplants
Bone and Bones
Therapeutics
Ameloblastoma
Statistical Data Interpretation
Bone Transplantation
Patient Selection
Neoplasms
Cohort Studies
Retrospective Studies

ASJC Scopus subject areas

  • Oral Surgery
  • Otorhinolaryngology
  • Surgery
  • Medicine(all)

Cite this

Is immediate reconstruction of the mandible with nonvascularized bone graft following resection of benign pathology a viable treatment option? / Schlieve, Thomas; Hull, William; Miloro, Michael; Kolokythas, Antonia.

In: Journal of Oral and Maxillofacial Surgery, Vol. 73, No. 3, 01.01.2015, p. 541-549.

Research output: Contribution to journalArticle

@article{9f0f3ea9ed674cb58dd9580b96b52ec4,
title = "Is immediate reconstruction of the mandible with nonvascularized bone graft following resection of benign pathology a viable treatment option?",
abstract = "Purpose The purpose of this study was to address the following clinical question: Is immediate reconstruction of the mandible with a nonvascularized bone graft after resection of benign pathology a viable treatment option? Another purpose was to determine whether any variables affect the success of this treatment approach. Materials and Methods The authors implemented a retrospective cohort study from a sample of patients diagnosed with a benign tumor of the mandible who were treated with segmental resection and primary reconstruction with an autogenous nonvascularized bone graft. The predictor variables were age, gender, lesion size, and diagnosis, and the outcome variable was graft success determined by re-establishment of mandibular continuity with sufficient bone for implant placement. The χ2 test was used for statistical analysis of the categorical data and P values less than.05 were considered statistically significant. Results Twenty patients with benign mandibular tumors were treated with transoral resection and immediate reconstruction with nonvascularized bone grafts. The mean age was 28.3 years (range, 9 to 63 yr) and 55{\%} (11 of 20) were men. The most common lesion type was ameloblastoma (13 of 20) and all patients underwent reconstruction with autogenous anterior iliac crest bone grafting. Ninety percent of patients (18 of 20) had successful reconstruction. Ten patients underwent successful implant placement and restoration. Conclusions Using careful patient selection, treatment of benign pathology with transoral resection and immediate reconstruction with a nonvascularized bone graft from the anterior iliac crest can be successful. In addition, the total treatment time from implant restoration to return to preoperative function is minimized. Therefore, this method of treatment is a viable treatment option and an alternative to delayed reconstruction or reconstruction with vascularized bone flaps.",
author = "Thomas Schlieve and William Hull and Michael Miloro and Antonia Kolokythas",
year = "2015",
month = "1",
day = "1",
doi = "10.1016/j.joms.2014.10.019",
language = "English (US)",
volume = "73",
pages = "541--549",
journal = "Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons",
issn = "0278-2391",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Is immediate reconstruction of the mandible with nonvascularized bone graft following resection of benign pathology a viable treatment option?

AU - Schlieve, Thomas

AU - Hull, William

AU - Miloro, Michael

AU - Kolokythas, Antonia

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Purpose The purpose of this study was to address the following clinical question: Is immediate reconstruction of the mandible with a nonvascularized bone graft after resection of benign pathology a viable treatment option? Another purpose was to determine whether any variables affect the success of this treatment approach. Materials and Methods The authors implemented a retrospective cohort study from a sample of patients diagnosed with a benign tumor of the mandible who were treated with segmental resection and primary reconstruction with an autogenous nonvascularized bone graft. The predictor variables were age, gender, lesion size, and diagnosis, and the outcome variable was graft success determined by re-establishment of mandibular continuity with sufficient bone for implant placement. The χ2 test was used for statistical analysis of the categorical data and P values less than.05 were considered statistically significant. Results Twenty patients with benign mandibular tumors were treated with transoral resection and immediate reconstruction with nonvascularized bone grafts. The mean age was 28.3 years (range, 9 to 63 yr) and 55% (11 of 20) were men. The most common lesion type was ameloblastoma (13 of 20) and all patients underwent reconstruction with autogenous anterior iliac crest bone grafting. Ninety percent of patients (18 of 20) had successful reconstruction. Ten patients underwent successful implant placement and restoration. Conclusions Using careful patient selection, treatment of benign pathology with transoral resection and immediate reconstruction with a nonvascularized bone graft from the anterior iliac crest can be successful. In addition, the total treatment time from implant restoration to return to preoperative function is minimized. Therefore, this method of treatment is a viable treatment option and an alternative to delayed reconstruction or reconstruction with vascularized bone flaps.

AB - Purpose The purpose of this study was to address the following clinical question: Is immediate reconstruction of the mandible with a nonvascularized bone graft after resection of benign pathology a viable treatment option? Another purpose was to determine whether any variables affect the success of this treatment approach. Materials and Methods The authors implemented a retrospective cohort study from a sample of patients diagnosed with a benign tumor of the mandible who were treated with segmental resection and primary reconstruction with an autogenous nonvascularized bone graft. The predictor variables were age, gender, lesion size, and diagnosis, and the outcome variable was graft success determined by re-establishment of mandibular continuity with sufficient bone for implant placement. The χ2 test was used for statistical analysis of the categorical data and P values less than.05 were considered statistically significant. Results Twenty patients with benign mandibular tumors were treated with transoral resection and immediate reconstruction with nonvascularized bone grafts. The mean age was 28.3 years (range, 9 to 63 yr) and 55% (11 of 20) were men. The most common lesion type was ameloblastoma (13 of 20) and all patients underwent reconstruction with autogenous anterior iliac crest bone grafting. Ninety percent of patients (18 of 20) had successful reconstruction. Ten patients underwent successful implant placement and restoration. Conclusions Using careful patient selection, treatment of benign pathology with transoral resection and immediate reconstruction with a nonvascularized bone graft from the anterior iliac crest can be successful. In addition, the total treatment time from implant restoration to return to preoperative function is minimized. Therefore, this method of treatment is a viable treatment option and an alternative to delayed reconstruction or reconstruction with vascularized bone flaps.

UR - http://www.scopus.com/inward/record.url?scp=84922612091&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84922612091&partnerID=8YFLogxK

U2 - 10.1016/j.joms.2014.10.019

DO - 10.1016/j.joms.2014.10.019

M3 - Article

C2 - 25683044

AN - SCOPUS:84922612091

VL - 73

SP - 541

EP - 549

JO - Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

JF - Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

SN - 0278-2391

IS - 3

ER -