Is there a role for growth hormone in the clinical management of burn injuries?

R. J. Ramirez, S. E. Wolf, D. N. Herndon

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

GH is a potent anabolic agent that offers distinct advantages to the hypercatabolic paediatric burns patient. GH can be administered with minimal risk of untoward side-effects in this patient group. GH reduces the catabolic effects of trauma, both directly and indirectly, through stimulation of protein synthesis. Accelerated wound healing and reduction in tissue-wasting effects are clear benefits that reduce the overall morbidity associated with burn injury in children. Further applications of GH treatment will stem from ongoing investigations that are examining alternative delivery methods, long- term treatment beyond the acute hospitalization phase, and combination therapy with β-blockers, antiglucocorticoids or other growth factors.

Original languageEnglish (US)
Pages (from-to)99-105
Number of pages7
JournalGrowth Hormone and IGF Research
Volume8
Issue numberSUPPL. B
StatePublished - 1998

Fingerprint

Growth Hormone
Wounds and Injuries
Anabolic Agents
Burns
Wound Healing
Intercellular Signaling Peptides and Proteins
Hospitalization
Therapeutics
Pediatrics
Morbidity
Proteins

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Is there a role for growth hormone in the clinical management of burn injuries? / Ramirez, R. J.; Wolf, S. E.; Herndon, D. N.

In: Growth Hormone and IGF Research, Vol. 8, No. SUPPL. B, 1998, p. 99-105.

Research output: Contribution to journalArticle

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