Isolated Mitral Cleft in Trisomy 21: An Initially ‘Silent’ Lesion

Poonam P. Thankavel; Claudio Ramaciotti

doi:10.1007/s00246-015-1291-5

Isolated Mitral Cleft in Trisomy 21: An Initially ‘Silent’ Lesion

Poonam P. Thankavel, Claudio Ramaciotti

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Congenital cardiac anomalies are common in trisomy 21, and transthoracic echocardiogram within the first month of life is recommended. While a cleft mitral valve associated with atrioventricular septal defect has been well defined in this population, the prevalence of isolated mitral valve cleft has not been previously reported. The aim of our study was to define the occurrence of isolated mitral cleft in the first echocardiogram of patients with trisomy 21. This retrospective chart review examined echocardiographic data on all Trisomy 21 patients

Original language	English (US)
Pages (from-to)	405-408
Number of pages	4
Journal	Pediatric Cardiology
Volume	37
Issue number	2
DOIs	https://doi.org/10.1007/s00246-015-1291-5
State	Published - Feb 1 2016

Keywords

Cleft
Down syndrome
Isolated mitral cleft
Trisomy 21

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Pediatrics, Perinatology, and Child Health

Access to Document

10.1007/s00246-015-1291-5

Cite this

@article{4983cc62080748188105011b1e952d19,

title = "Isolated Mitral Cleft in Trisomy 21: An Initially {\textquoteleft}Silent{\textquoteright} Lesion",

abstract = "Congenital cardiac anomalies are common in trisomy 21, and transthoracic echocardiogram within the first month of life is recommended. While a cleft mitral valve associated with atrioventricular septal defect has been well defined in this population, the prevalence of isolated mitral valve cleft has not been previously reported. The aim of our study was to define the occurrence of isolated mitral cleft in the first echocardiogram of patients with trisomy 21. This retrospective chart review examined echocardiographic data on all Trisomy 21 patients ",

keywords = "Cleft, Down syndrome, Isolated mitral cleft, Trisomy 21",

author = "Thankavel, {Poonam P.} and Claudio Ramaciotti",

year = "2016",

month = feb,

day = "1",

doi = "10.1007/s00246-015-1291-5",

language = "English (US)",

volume = "37",

pages = "405--408",

journal = "Pediatric Cardiology",

issn = "0172-0643",

publisher = "Springer New York",

number = "2",

}

TY - JOUR

T1 - Isolated Mitral Cleft in Trisomy 21

T2 - An Initially ‘Silent’ Lesion

AU - Thankavel, Poonam P.

AU - Ramaciotti, Claudio

PY - 2016/2/1

Y1 - 2016/2/1

N2 - Congenital cardiac anomalies are common in trisomy 21, and transthoracic echocardiogram within the first month of life is recommended. While a cleft mitral valve associated with atrioventricular septal defect has been well defined in this population, the prevalence of isolated mitral valve cleft has not been previously reported. The aim of our study was to define the occurrence of isolated mitral cleft in the first echocardiogram of patients with trisomy 21. This retrospective chart review examined echocardiographic data on all Trisomy 21 patients

AB - Congenital cardiac anomalies are common in trisomy 21, and transthoracic echocardiogram within the first month of life is recommended. While a cleft mitral valve associated with atrioventricular septal defect has been well defined in this population, the prevalence of isolated mitral valve cleft has not been previously reported. The aim of our study was to define the occurrence of isolated mitral cleft in the first echocardiogram of patients with trisomy 21. This retrospective chart review examined echocardiographic data on all Trisomy 21 patients

KW - Cleft

KW - Down syndrome

KW - Isolated mitral cleft

KW - Trisomy 21

UR - http://www.scopus.com/inward/record.url?scp=84959564153&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84959564153&partnerID=8YFLogxK

U2 - 10.1007/s00246-015-1291-5

DO - 10.1007/s00246-015-1291-5

M3 - Article

C2 - 26481224

AN - SCOPUS:84959564153

SN - 0172-0643

VL - 37

SP - 405

EP - 408

JO - Pediatric Cardiology

JF - Pediatric Cardiology

IS - 2

ER -

Isolated Mitral Cleft in Trisomy 21: An Initially ‘Silent’ Lesion

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this