Isolated thrombocytopenia in children with acute lymphoblastic leukemia

A rare event in a Pediatric Oncology Group Study

A. S. Dubansky, J. M. Boyett, J. Falletta, D. H. Mahoney, V. J. Land, J. Pullen, G. Buchanan

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

To determine how many children with acute lymphoblastic leukemia initially referred to a pediatric hematologist because of isolated significant thrombocytopenia ([platelet count <50000/mm3] and an otherwise normal complete blood cell count and physical findings), a retrospective review of the Pediatric Oncology Group's charts was undertaken. Review of the records of 2239 children enrolled in the past two acute lymphoblastic leukemia protocols showed that none of these children had significant thrombocytopenia with no other hematologic or physical manifestations of acute lymphoblastic leukemia when they were first seen by the hematologist. The results suggest that routine bone marrow aspiration in the child with isolated thrombocytopenia may be unnecessary to rule out acute lymphocytic leukemia.

Original languageEnglish (US)
Pages (from-to)1068-1071
Number of pages4
JournalPediatrics
Volume84
Issue number6
StatePublished - 1989

Fingerprint

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Thrombocytopenia
Pediatrics
Blood Cell Count
Platelet Count
Bone Marrow

Keywords

  • acute lymphoblastic leukemia
  • idiopathic thrombocytopenic purpura

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Dubansky, A. S., Boyett, J. M., Falletta, J., Mahoney, D. H., Land, V. J., Pullen, J., & Buchanan, G. (1989). Isolated thrombocytopenia in children with acute lymphoblastic leukemia: A rare event in a Pediatric Oncology Group Study. Pediatrics, 84(6), 1068-1071.

Isolated thrombocytopenia in children with acute lymphoblastic leukemia : A rare event in a Pediatric Oncology Group Study. / Dubansky, A. S.; Boyett, J. M.; Falletta, J.; Mahoney, D. H.; Land, V. J.; Pullen, J.; Buchanan, G.

In: Pediatrics, Vol. 84, No. 6, 1989, p. 1068-1071.

Research output: Contribution to journalArticle

Dubansky, AS, Boyett, JM, Falletta, J, Mahoney, DH, Land, VJ, Pullen, J & Buchanan, G 1989, 'Isolated thrombocytopenia in children with acute lymphoblastic leukemia: A rare event in a Pediatric Oncology Group Study', Pediatrics, vol. 84, no. 6, pp. 1068-1071.
Dubansky AS, Boyett JM, Falletta J, Mahoney DH, Land VJ, Pullen J et al. Isolated thrombocytopenia in children with acute lymphoblastic leukemia: A rare event in a Pediatric Oncology Group Study. Pediatrics. 1989;84(6):1068-1071.
Dubansky, A. S. ; Boyett, J. M. ; Falletta, J. ; Mahoney, D. H. ; Land, V. J. ; Pullen, J. ; Buchanan, G. / Isolated thrombocytopenia in children with acute lymphoblastic leukemia : A rare event in a Pediatric Oncology Group Study. In: Pediatrics. 1989 ; Vol. 84, No. 6. pp. 1068-1071.
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