Langerhans cell surface densities in rat oral mucosa and human buccal mucosa

E. E. Ahlfors; P. A. Larsson; P. R. Bergstresser

doi:10.1111/j.1600-0714.1985.tb00510.x

Langerhans cell surface densities in rat oral mucosa and human buccal mucosa

E. E. Ahlfors, P. A. Larsson, P. R. Bergstresser

Dermatology

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

We determined surface densities of Langerhans cells (LCs) in rat oral mucosa and human buccal mucosa by enumerating ATPase‐positive dendritic cells in epithelial whole mounts. For the rat, mean surface densities per mm² were 160 in anterior buccal mucosa, 640 in posterior buccal mucosa, 430 in the palate and 340 in the tongue. Human buccal mucosa showed a density of 890 cells per mm². We conclude that LC densities in oral mucosa approximate those of external body sites, making them available in numbers sufficient to accomplish their postulated antigen‐presenting functions.

Original language	English (US)
Pages (from-to)	390-397
Number of pages	8
Journal	Journal of Oral Pathology & Medicine
Volume	14
Issue number	5
DOIs	https://doi.org/10.1111/j.1600-0714.1985.tb00510.x
State	Published - May 1985

ASJC Scopus subject areas

Pathology and Forensic Medicine
Oral Surgery
Otorhinolaryngology
Cancer Research
Periodontics

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10.1111/j.1600-0714.1985.tb00510.x

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abstract = "We determined surface densities of Langerhans cells (LCs) in rat oral mucosa and human buccal mucosa by enumerating ATPase‐positive dendritic cells in epithelial whole mounts. For the rat, mean surface densities per mm2 were 160 in anterior buccal mucosa, 640 in posterior buccal mucosa, 430 in the palate and 340 in the tongue. Human buccal mucosa showed a density of 890 cells per mm2. We conclude that LC densities in oral mucosa approximate those of external body sites, making them available in numbers sufficient to accomplish their postulated antigen‐presenting functions.",

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AB - We determined surface densities of Langerhans cells (LCs) in rat oral mucosa and human buccal mucosa by enumerating ATPase‐positive dendritic cells in epithelial whole mounts. For the rat, mean surface densities per mm2 were 160 in anterior buccal mucosa, 640 in posterior buccal mucosa, 430 in the palate and 340 in the tongue. Human buccal mucosa showed a density of 890 cells per mm2. We conclude that LC densities in oral mucosa approximate those of external body sites, making them available in numbers sufficient to accomplish their postulated antigen‐presenting functions.

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Langerhans cell surface densities in rat oral mucosa and human buccal mucosa

Abstract

ASJC Scopus subject areas

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